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(E)-1-[2-(acetylamino)ethylidene]-7-methoxy-1,2,3,4tetrahydronaphthalene, also known as Agomelatine Impurity 2, is a chemical compound derived from the melatoninergic agonist Agomelatine (A430000). It is characterized by its unique structure, which includes an acetylaminoethylidene group and a methoxy substituent on a tetrahydronaphthalene core. This impurity is found in Agomelatine, a medication used for the treatment of major depressive disorder.

178677-39-9

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178677-39-9 Usage

Uses

Used in Pharmaceutical Industry:
(E)-1-[2-(acetylamino)ethylidene]-7-methoxy-1,2,3,4tetrahydronaphthalene is used as an impurity in Agomelatine, a medication for the treatment of major depressive disorder. As an impurity, it is important to monitor and control its presence in the final product to ensure the safety and efficacy of the medication. The presence of this impurity may affect the pharmacological properties and therapeutic outcomes of Agomelatine, making it crucial to maintain its levels within acceptable limits as per regulatory guidelines.

Check Digit Verification of cas no

The CAS Registry Mumber 178677-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,6,7 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 178677-39:
(8*1)+(7*7)+(6*8)+(5*6)+(4*7)+(3*7)+(2*3)+(1*9)=199
199 % 10 = 9
So 178677-39-9 is a valid CAS Registry Number.

178677-39-9Downstream Products

178677-39-9Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF N-[2- (7-METHOXY-L-NAPHTHYL) ETHYL] ACETAMIDE AND ITS NOVEL CRYSTALLINE FORMS

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Page/Page column 26; 30; 31, (2012/04/23)

The present invention relates to a process for the preparation of N-[2-(7-methoxy-l-naphthyl)ethyl]acetamide compound of formula-1 and novel crystalline forms of its intermediates as well as the final compound.

Benzocycloalkene compounds, their production and use

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, (2008/06/13)

A compound of the formula wherein R1and R2are H, a hydrocarbon group or a heterocyclic group, or R1and R2are combinedly a spiro ring; R3is a hydrocarbon group, a substituted amino group, a substituted

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