178681-99-7Relevant academic research and scientific papers
Synthesis of some new pyrimidothienopyridazines and related heterocycles
Radwan,Kamal El-Dean,Bakhite
, p. 303 - 308 (2007/10/03)
5-Amino-3,4-diphenylthieno[2,3-c]pyridazine-6-carbonitrile 2a was reacted with propylene diamine to give tetrahydropyrimidinyl derivative 3. The latter compound (3) underwent certain cyclocondensation reactions to produce pyrimidothienopyridazines 4-6. Al
Pyridazine Derivatives: Some Reactions of 5-Aminothieno[2,3-c]pyridazine-6-carbonitriles, Synthesis of New Condensed Pyrimido and Triazinothienopyridazines
Radwan, Sh. M.
, p. 175 - 188 (2007/10/03)
3,4-Difuryl or 3,4-diphenyl-5-aminothieno[2,3-c]pyridazine-6-carbonitriles 2a,b were prepared and subjected to some sequence reactions to afford new condensed polycyclic compounds containing thieno[2,3-c]pyridazines with anticipated biological activity.
A General Route for the Synthesis of Pyrimidothienopyridazine Derivatives
Quintela, J. M.,Veiga, M. C.,Conde, S.,Peinador, C.
, p. 739 - 746 (2007/10/03)
A facile synthesis of 8-substituted pyrimidothienopyridazines (6a-i) has been accomplished.The sequence involves the ring closure of a heterocyclic aminonitrile precursor (3) after reaction with (dichlomethylene)-dimethylammonium chloride. - Keywords: Pyrimidothienopyridazine derivatives; Thienopyridazine-6-carbonitrile; N,N-Dimethyldichloromethyleniminium chloride; Enaminonitrile
