178889-47-9Relevant articles and documents
Method for preparing linear alkyl cyclohexyl acrylate through one-pot process
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Paragraph 0039-0050, (2019/02/04)
The invention relates to a method for preparing linear alkyl cyclohexyl acrylate through a one-pot process. The method is characterized by comprising the following step: under inert atmosphere, enabling a Grignard reagent based on linear alkyl cyclohexano
Catalytic acryloxypalladation of vinylcycloalkanes and exo-methylene cycloalkanes. Mechanistic insights into the competition between allylic acryloxypalladation and formation of a-methylene y-butyrolactones
Ferret, Nicolas,Mussate-Mathieu, Laurence,Perfetti, Patricia,Zahra, Jean-Pierre,Waegell, Bernard
, p. 1023 - 1031 (2007/10/03)
Acryloxypalladation of ezo-methylenecycloalkanes (three-, four-, five- and six-membered rings) and vinylcycloalkanes (three-, five- and six-membered rings) in the presence of the Pd(OAc)2/p-benzoquinone/MnC>2 catalytic system is reported. Except for the case of eio-methylenecyclopropane, this reaction provides a rapid entry to the corresponding Q-metliylene -/-butyrolactone, which essentially results from a 1,2-Markovnikov acryloxypalladation addition on the double bond. The subsequent insertion of the acrylate double bond into the carbon-palladium bond is followed by a β-elimination step. However, this reaction competes with the formation of intermediate -allyl complexes which yields the corresponding allylic acrylates. The ratio of butyrolactones to allylic acrylates is dependent on ring size. Elsevier,.