178945-27-2

Usage

Molecular structure

1H-Indole-1-carboxylic acid, 3-[2,5-dihydro-1-methyl-2,5-dioxo-4-[5-(phenylmethoxy)-1H-indol-3-yl]-1H-pyrrol-3-yl]-6-(phenylmethoxy)-, 1,1-dimethylethyl ester is a complex organic compound with an indole ring, a pyrrole ring, and multiple functional groups attached to it.

Functional groups

The compound contains an indole carboxylic acid group (-COOH), a t-butyl ester group (-OC(CH3)3), phenylmethoxy groups (-OCH2Ph), and a pyrrol-3-yl group.

Stereochemistry

The compound has a 2,5-dihydro-1-methyl-2,5-dioxo-4moiety, which indicates the presence of a six-membered ring with two hydrogen atoms in the 2 and 5 positions, a methyl group at the 1 position, and two oxygen atoms in the 2 and 5 positions.

Potential applications

Due to its complex structure and functional groups, 1H-Indole-1-carboxylic acid, 3-[2,5-dihydro-1-methyl-2,5-dioxo-4-[5-(phenylmethoxy)-1H-indol-3-yl]-1 H-pyrrol-3-yl]-6-(phenylmethoxy)-, 1,1-dimethylethyl ester may have potential applications in pharmaceuticals or organic synthesis.

Further research

To determine the specific properties and potential uses of 1H-Indole-1-carboxylic acid, 3-[2,5-dihydro-1-methyl-2,5-dioxo-4-[5-(phenylmethoxy)-1H-indol-3-yl]-1 H-pyrrol-3-yl]-6-(phenylmethoxy)-, 1,1-dimethylethyl ester, further research and testing would be necessary. This includes analyzing its solubility, stability, reactivity, and biological activity.

Upstream product

• 1215-59-4 5-benzyloxy-1H-indole 
• 174402-44-9 tert-butyl 6-(benzyloxy)-3-(4-bromo-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl)-1H-indole-1-carboxylate 
• 2581-34-2 3-methyl-4-nitrophenol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 100-44-7 benzyl chloride 
• 153805-85-7 1-[(E)-2-(5-benzyloxy-2-nitrophenyl)vinyl]pyrrolidine 
• 174402-43-8 3-(6-benzyloxy-1H-indol-3-yl)-4-bromo-1-methyl-pyrrole-2,5-dione 

Downstream Products

• 848086-47-5 3-(6-Benzyloxy-1H-indol-3-yl)-4-[5-benzyloxy-1-((2R,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-1-methyl-pyrrole-2,5-dione 
• 848086-46-4 6-benzyloxy-3-{4-[5-benzyloxy-1-(3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yl)-1H-indol-3-yl]-1-methyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl}-indole-1-carboxylic acid tert-butyl ester 
• 178945-29-4 2,5-dihydro-3-(5-benzyloxy-1H-indol-3-yl)-4-(6-benzyloxy-1H-indol-3-yl)-1-methyl-1H-pyrrole-2,5-dione 

Relevant academic research and scientific papers

Synthesis and biological activities of NB-506 analogues: Effects of the positions of two hydroxyl groups at the indole rings

In the course of a study of 6-N-amino-substituted analogues of NB-506 (1), a more potent anticancer drag, J-109,404 (2), in which the formyl group of NB-506 was replaced with a 1,3-dihydroxypropane group, was reported. A study of further modification in the positions of two hydroxyl groups at the indole rings of 2 resulted in the discovery of a 2,10-dihydroxy analogue, J- 107,088 (3), which is a promising anticancer agent with a broader therapeutic window than J-109,404.

Practical synthesis of indolopyrrolocarbazoles

A practical method for the synthesis of an indolo[2,3-a]pyrrolo[3,4- c]carbazole ring system is described. The method involves two key processes: a coupling reaction between indole and substituted methylmaleimide portions using lithium hexamethyldisilazide (LiHMDS) as a base, and the oxidative cyclization of bisindolylmaleimide with palladium (II) chloride. We applied this method to the synthesis of arcyriaflavin B (5), C (6) and D (7).