178984-69-5

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 4-chloroquinoline-7-carboxylate is used as an intermediate in the synthesis of various pharmaceutical drugs and active ingredients. Its unique chemical structure and properties contribute to the development of new medications with potential therapeutic benefits.
Used in Agrochemical Development:
Methyl 4-chloroquinoline-7-carboxylate is utilized in the development of agrochemicals, where it serves as a key component in the creation of effective and targeted pest control solutions, enhancing crop protection and yield.
Used in Specialty Chemicals Production:
In the specialty chemicals industry, methyl 4-chloroquinoline-7-carboxylate is employed as a valuable building block for the production of a variety of chemical products. Its versatile nature allows for its incorporation into different chemical formulations, catering to specific industrial needs and applications.

Upstream product

• 67-56-1 methanol 
• 346-55-4 4-chloro-7-trifluoromethyl quinoline 
• 1374258-80-6 methyl quinoline-7-carboxylate 1-oxide 
• 51552-68-2 quinoline-7-carboxylic acid methyl ester 
• 1078-30-4 quinoline-7-carboxylic acid 
• 863785-96-0 methyl 4-oxo-1H-quinoline-7-carboxylate 
• 49713-58-8 4‐chloroquinoline‐7‐carboxylic acid 
• 74-88-4 methyl iodide 

Downstream Products

• 49713-58-8 4‐chloroquinoline‐7‐carboxylic acid 
• 1150618-22-6 4-hydroxyquinoline-7-carboxylic acid 
• 178984-42-4 4-chloroquinoline-7-carboxylic acid amide 

Relevant academic research and scientific papers

COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS

Disclosed herein are compounds of Formula (I) which inhibit, regulate and/or modulate tyrosine kinase receptors, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities, compositions containing the compounds, methods of using the compounds to treat kinase-dependent diseases and conditions, and methods for making the compounds.

TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS

Compounds of Formula (I) are useful as antagonists of TRPM8. Such compounds are useful in treating a number of TRPM8 mediated disorders and conditions and may be used to prepare medicaments and pharmaceutical compositions useful for treating such disorders and conditions. Examples of such disorders include, but are not limited to, migraines and neuropathic pain. Compounds of Formula (I) have a structure where the definitions of the variables are provided herein.

COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME

The present invention provides compounds of formula (I) or compounds of formula (II) and pharmaceutically acceptable salts or solvates thereof. An objective of the present invention is to provide compounds having TGF2 inhibitory activity.

Substituted oxoazaheterocyclyl compounds

This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa..

Thioquinolone compounds which have useful pharmaceutical activity

Disclosed is a thioquinolone derivative which exhibits highly selective antibacterial activity against Helicobacter pylori.