178985-92-7

Upstream product

• 185946-32-1 (E)-5-(1-Hydroxy-2,2,6-trimethyl-cyclohexyl)-3-methyl-pent-2-en-4-ynoic acid methyl ester 
• 41613-59-6 1-ethynyl-2,2,6-trimethyl-1-cyclohexanol 
• 23326-27-4 Methyl 2-butynoate 

Downstream Products

• 74976-66-2 3-methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-2-en-4-yn-1-ol 
• 178985-94-9 1,3,3-Trimethyl-2-((E)-3-methyl-hex-3-ene-1,5-diynyl)-cyclohexene 
• 69037-20-3 5-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-methyl-(E)-2-penten-4-yn-al 

Relevant academic research and scientific papers

Palladium-catalyzed additions of terminal alkynes to acceptor alkynes

The development of addition reactions wherein the product is the simple sum of the reactants plus anything else (only needed catalytically) constitutes an important goal for enhanced synthetic efficiency. The C-H bond of terminal alkynes (the donor alkyne

Iterative PD catalyzed additions for a synthesis of methyl 7,8,11,12 tetradehydroretinoate

A 6 step synthesis of the title compound derives from a palladium catalyzed addition of terminal alkynes to acceptor alkynes.