179083-21-7Relevant articles and documents
Conversion of acyclic nonpeptide CCK antagonists into CCK agonists
Hirst, Gavin C.,Queen, Kennedy L.,Sugg, Elizabeth E.,Willson, Timothy M.
, p. 511 - 514 (1997)
The CCK antagonists RP 69758 and (R)-lorglumide were converted into CCK agonists by the introduction of an N-isopropylanilide agonist 'trigger'. The common structural features of these ligands suggest that nonpeptide agonists and antagonists bind to a common site in the CCK receptor.