1792-36-5

Basic information

• Product Name: 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI)
• Synonyms: 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI)
• CAS NO: 1792-36-5
• Molecular Formula: C12H10N2
• Molecular Weight: 182.2212
• Product Categories: BENZIMIDAZOLE
• Mol File: 1792-36-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI)(1792-36-5)
• EPA Substance Registry System: 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI)(1792-36-5)

Safety Data

• Hazardous Substances Data: 1792-36-5(Hazardous Substances Data)

Usage

1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI) properties and specific content

A chemical compound consisting of 14 carbon atoms, 10 hydrogen atoms, and 2 nitrogen atoms.

Derivative of imidazole

A modified version of the imidazole molecule, which is a heterocyclic aromatic organic compound.

Naphthalene ring structure

Contains a fused benzene ring system, with two six-carbon rings connected by shared carbon atoms, contributing to its stability and aromaticity.

Methyl group attachment at the 2-position

A single carbon atom (methyl group) is attached to the second carbon position of the imidazole ring, influencing its chemical reactivity and properties.

Industrial applications

Utilized as a building block for the synthesis of other organic compounds, making it a valuable component in various chemical reactions and processes.

Potential biological activities

Possesses possible antifungal and antibacterial properties, suggesting potential use in pharmaceuticals or other biological applications.

Need for further research

More studies are required to fully understand the properties, potential uses, and safety of 1H-Naphth[2,3-d]imidazole,2-methyl-(7CI,9CI).

Upstream product

• 771-97-1 2,3-Diaminonaphthalene 
• 78-39-7 Triethyl orthoacetate 
• 64-19-7 acetic acid 
• 92-44-4 2,3-naphthalenediol 

Downstream Products

• 4572-59-2 1,2-dimethyl-1H-naphtho[2,3-d]imidazole-4,9-dione 
• 71675-75-7 1,2-dimethyl-1H-naphtho-[2,3-d]imidazole 
• 139167-52-5 1,3-diethyl-2-<3-(1-ethylbenzindol-2(1H)-ylidene)-1-propenyl>-1H-naphth<2,3-d>imidazolium chloride 
• 139167-47-8 1,3-diethyl-2-<3-(1,3-dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl>-1H-naphth<2,3-d>imidazolium chloride 

Relevant articles and documents

Oxidation products of fused 2-hetarylimidazole derivatives

Oxidation of 5-(1-methyl-1H-benzimidazol-2-yl)thiophene-, and -selenophene-2-carbaldehydes with potassium dichromate in 20% aqueous sulfuric acid afforded the corresponding carboxylic acids. Analogous reaction with 5-(1-methyl-1H-benzimidazol-2-yl)furan-2-carbaldehyde led to the formation of 1- methyl-1H-benzimidazole as a result of decarboxylation of the primary oxidation product and subsequent decomposition of the furan ring. Probable factors responsible for instability of 5-(1H-benzimidazol-2-yl)- hetarene-2-carboxylic acids were considered. The oxidation of 2-furylnaphtho[2,3-d]- and 2-hetarylphenanthro- [9,10-d]imidazoles gave, respectively, an anthraquinone analog and 6,7-quinones. ?-Electron-rich heterocycles in 2-furyl- and 2-pyrrolylphenanthro[9,10-d]imidazoles were oxidized completely, being replaced by hydrogen. Pleiades Publishing, Ltd., 2011.

Synthesis and substance P antagonist activity of naphthimidazolium derivatives

The synthesis of unsymmetrical naphth[2,3-d]imidazolium and bridged naphth[2,3-d]imidazolium derivatives and their substance P (SP) antagonist activity are described. All compounds were evaluated for their ability to displace SP from neurokinin-1 (NK-1) receptor sites using standard receptor binding methodology (rat forebrain membrane). 1,3-Diethyl-2-[3-(1,3-dihydro- 1,3,3-trimethyl-2H-indol-2-ylidene)-1-propenyl]-1H-naphth[2,3-d]imidazolium chloride (7a), a representative compound in this series, was further evaluated for SP antagonist activity in a guinea pig ileum contractility assay. In vivo SP antagonist activity of 7a was demonstrated using SP-induced salivation and paw edema models performed in rats.