17924-66-2

Basic information

• Product Name: phenyl-6 hexene-5 ol-1 (E)
• Synonyms: phenyl-6 hexene-5 ol-1 (E)
• CAS NO: 17924-66-2
• Molecular Weight: 176.258
• Mol File: 17924-66-2.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: phenyl-6 hexene-5 ol-1 (E)(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl-6 hexene-5 ol-1 (E)(17924-66-2)
• EPA Substance Registry System: phenyl-6 hexene-5 ol-1 (E)(17924-66-2)

Safety Data

• Hazardous Substances Data: 17924-66-2(Hazardous Substances Data)

Upstream product

• 821-41-0 5-Hexen-1-ol 
• 591-50-4 iodobenzene 
• 100-52-7 benzaldehyde 
• 34626-52-3 5-hydroxypentyltriphenylphosphonium bromide 
• 4066-82-4 1-phenyl-hexane-1,6-diol 
• 4221-03-8 5-hydroxypentanal 
• 100-39-0 benzyl bromide 
• 69936-53-4 6-phenylhex-5-yn-1-ol 
• 34626-51-2 5-bromopentan-1-ol 
• 15848-22-3 5-bromo-1-pentanyl acetate 
• 142-68-7 TETRAHYDROPYRANE 
• 2396-80-7 methyl 5-hexenoate 
• 85396-64-1 (E)-6-phenyl-5-hexenoic acid methyl ester 
• 108-86-1 bromobenzene 

Downstream Products

• 197707-45-2 methanesulfonate of 6-phenyl-(5E)-hexenol 
• 13664-87-4 trans-6-Phenyl-hexen-⁽⁵⁾-yl-⁽¹⁾-p-brom-benzolsulfonat 
• 36884-77-2 trans-6-phenyl-5-hexenal 
• 205746-41-4 ((E)-6-Azido-hex-1-enyl)-benzene 
• 57238-66-1 (E)-7-phenylhept-6-en-2-one 
• 13664-89-6 6-Phenyl-hexyl-p-brom-benzolsulfonat 
• 128577-79-7 3-[3-(2-Ethoxycarbonyl-ethyl)-4-((E)-6-phenyl-hex-5-enyloxy)-benzoyl]-benzoic acid ethyl ester 
• 128578-05-2 3-[3-(2-Carboxy-ethyl)-4-((E)-6-phenyl-hex-5-enyloxy)-benzoyl]-benzoic acid 
• 157723-90-5 E-6-iodo-1-phenyl-1-hexene 
• 148470-67-1 (E)-6-(benzylthio)-1-phenyl-1-hexene 
• 220791-77-5 (E)-1-<2-(methoxymethoxy)-3,6-dimethylphenyl>-6-phenyl-5-hexen-1-ol 
• 220791-76-4 (E)-1-<2-methoxy-6-(methoxymethoxy)phenyl>-6-phenyl-5-hexen-1-ol 
• 220791-78-6 (E)-1-<5-bromo-2-(methoxymethoxy)phenyl>-6-phenyl-5-hexen-1-ol 

Relevant articles and documents

Tandem Pd-catalyzed C-C coupling/recyclization of 2-(2-bromoaryl)cyclopropane-1,1-dicarboxylates with primary nitro alkanes

The first successful synthesis of 1H-2,3-benzoxazine 3-oxides has been described. The efficiency of the approach is provided by the C-C-coupling of 2-(2-bromoaryl)cyclopropane-1,1-dicarboxylates with primary nitroalkanes catalyzed by Pd(dba)2/JohnPhos system followed by in situ recyclization of the intermediates. Several representative transformations allowing selective modification of the nitronate as well as malonate functionalities in the resulting compounds are demonstrated.

Aminolithiation–arylation consecutive cyclization of N-(2-fluorophenyl)methylaminoalkylstyryls giving aryl-substituted pyrido[1,2-b]isoquinolines

Aminolithiation–arylation tandem cyclization of N-(2-fluorophenyl)methylaminoalkylstyryls proceeded smoothly to give hexahydro-2H-pyrido[1,2-b]isoquinoline using a stoichiometric amount of n-BuLi with high trans selectivity. The arylation reaction was highly accelerated by the addition of HMPA. Both pyrido- and pyrrolo-[1,2-b]isoquinoline were successfully constructed by this tandem reaction.

Photoredox Activation of SF6for Fluorination

We report the first practical use of SF6as a fluorinating reagent in organic synthesis. Photoredox catalysis enables the in situ conversion of SF6, an inert gas, into an active fluorinating species by using visible light. Under these conditions, deoxyfluorination of allylic alcohols is effected with high chemoselectivity and is tolerant of a wide range of functional groups. Application of the methodology in a continuous-flow setup achieves comparable yields to those obtained with a batch setup, while providing drastically increased material throughput of valuable allylic fluoride products.