179246-15-2

Basic information

• Product Name: 6,7-diethoxyquinazolin-4(3H)-one
• Synonyms: 6,7-diethoxyquinazolin-4(3H)-one;6,7-diethoxy-4(1H)-Quinazolinone;6,7-diethoxy-3,4-dihydroquinazolin-4-one;4(1H)-Quinazolinone, 6,7-diethoxy- (9CI);6,7-Diethoxy-3H-quinazolin-4-one;6,7-Diethoxyquinazolin-4-one;6,7-Diethoxyquinazolin-4(8H)-one
• CAS NO: 179246-15-2
• Molecular Formula: C₁₂H₁₄N₂O₃
• Molecular Weight: 234.25116
• EINECS: -0
• Mol File: 179246-15-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 248-251.5℃
• Appearance: /
• CAS DataBase Reference: 6,7-diethoxyquinazolin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-diethoxyquinazolin-4(3H)-one(179246-15-2)
• EPA Substance Registry System: 6,7-diethoxyquinazolin-4(3H)-one(179246-15-2)

Safety Data

• Hazardous Substances Data: 179246-15-2(Hazardous Substances Data)

Usage

General Description

6,7-diethoxyquinazolin-4(3H)-one is a chemical compound with a molecular formula C12H14N2O3. It belongs to the class of quinazolinone derivatives and is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. 6,7-diethoxyquinazolin-4(3H)-one has been studied for its potential use as a building block in drug discovery and development. It is known for its selective inhibitory effects on specific enzymes and receptors, which makes it a valuable tool in the field of medicinal chemistry. Additionally, 6,7-diethoxyquinazolin-4(3H)-one has also shown promise in the treatment of certain diseases and conditions, and its properties continue to be researched for potential applications in various industries.

Upstream product

• 460750-26-9 4,5-diethoxy-2-nitrobenzoic acid ethyl ester 
• 75332-44-4 3,4-diethoxybenzoic acid ethyl ester 
• 103796-34-5 2-nitro-4,5-diethoxybenzoic acid 
• 20197-71-1 4,5-diethoxy-2-aminobenzoic acid methyl ester 
• 5409-31-4 3,4-diethoxybenzoic acid 
• 20197-72-2 2-amino-4,5-diethoxybenzoic acid 
• 6313-33-3 formamidine hydrochloride 
• 77287-34-4 formamide 
• 460750-27-0 2-amino-4,5-diethoxybenzoic acid ethyl ester 

Downstream Products

• 162363-46-4 4-Chloro-6,7-diethoxyquinazoline 
• 451494-93-2 7-ethoxy-6-hydroxyquinazolin-4(3H)-one 
• 716314-61-3 2-bromo-1-[3-(6,7-diethoxy-quinazolin-4-ylamino)-phenyl]-ethanone 
• 774532-51-3 1-[3-(6,7-diethoxy-quinazolin-4-ylamino)-phenyl]-ethanone 

Relevant articles and documents

QUINAZOLINE DERIVATIVES AS RAF KINASE MODULATORS AND METHODS OF USE THEREOF

Compounds according to formula (I), compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. Formula (I): or a pharmaceutically acceptable salt, solvate, clathrate of hydrate thereof, wherein X is O or S(O)t; Ra is O or S.

Quinazoline derivatives and therapeutic use thereof

Quinazoline derivatives represented by the general formula pharmacologically acceptable salts thereof, and compositions containing such compounds are described. Methods for using the compounds for treatment of hyperproliferative disorders are also described.

Anilinoquinazoline inhibitors of fructose 1,6-bisphosphatase bind at a novel allosteric site: Synthesis, in vitro characterization, and x-ray crystallography

The synthesis and in vitro structure-activity relationships (SAR) of a novel series of anilinoquinazolines as allosteric inhibitors of fructose-1,6-bisphosphatase (F16Bpase) are reported. The compounds have a different SAR as inhibitors of F16Bpase than a