179246-23-2Relevant academic research and scientific papers
Efficient reducing system based on iron for conversion of nitroarenes to anilines
Xiao, Zhu-Ping,Wang, Ying-Chun,Du, Gao-Yu,Wu, Jun,Luo, Tao,Yi, Shou-Fu
experimental part, p. 661 - 665 (2011/03/19)
Reduction of nitroarenes with low solubility in EtOH-H2O to anilines easily occurs in a Fe-NH4Cl-acetone-H2O system, and treatment of the same nitroarenes with Fe-NH4Cl-EtOH-H2O hardly furnished the corresponding products. Under the reaction condition, the reducible or hydrolysable groups are not affected.
SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors
Leban, Johann,Kralik, Martin,Mies, Jan,Gassen, Michael,Tentschert, Karin,Baumgartner, Roland
, p. 4854 - 4857 (2007/10/03)
Novel DHODH inhibitors were developed based on a previously described series by introduction of heteroatoms into the cyclopentene ring and hydroxyl groups attached to it. Also, the hydrophobic biphenyl side chain was replaced with benzyloxy phenyl groups. Activities on human, rat, and mouse enzymes indicate a species specificity of these inhibitors.
