17927-88-7

Basic information

• Product Name: 2-(phenylsulfonyl)benzo[d]isothiazol-3(2H)-one
• CAS NO: 17927-88-7
• Molecular Weight: 291.351
• Mol File: 17927-88-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(phenylsulfonyl)benzo[d]isothiazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(phenylsulfonyl)benzo[d]isothiazol-3(2H)-one(17927-88-7)
• EPA Substance Registry System: 2-(phenylsulfonyl)benzo[d]isothiazol-3(2H)-one(17927-88-7)

Safety Data

• Hazardous Substances Data: 17927-88-7(Hazardous Substances Data)

Upstream product

• 19602-82-5 2,2'-dithiodibenzoic acid dichloride 
• 98-10-2 benzenesulfonamide 
• 110-86-1 pyridine 
• 2634-33-5 1,2-benzisothiazolin-3-one 
• 98-09-9 benzenesulfonyl chloride 
• 3950-02-5 2-chlorosulfenylbenzoyl chloride 
• 119-80-2 2,2'-dithiobenzoic acid 

Downstream Products

• 33923-98-7 2-amino-9H-thioxanthen-9-one 
• 50900-50-0 2-(4-amino-phenylsulfanyl)-benzoic acid 
• 860698-16-4 2-[4-(ethyl-methyl-amino)-phenylsulfanyl]-benzoic acid 
• 177786-68-4 2,2'-disulfanediyl-di-benzoic acid bis-benzenesulfonylamide 
• 80936-89-6 2-benzenesulfonyl-1,1-dioxo-1λ⁶-benz[d]isothiazol-3-one 
• 5556-20-7 ethyl 3-hydroxybenzothiophene-2-carboxylate 
• 857485-27-9 [2-(1-acetyl-2-oxo-propylsulfanyl)-benzoyl]-benzenesulfonyl-amine 
• 860680-99-5 2-(4-amino-phenylsulfanyl)-benzoic acid benzenesulfonylamide 
• 860681-12-5 2-[4-(benzyl-methyl-amino)-phenylsulfanyl]-benzoic acid benzenesulfonylamide 
• 860683-76-7 2-[4-(ethyl-methyl-amino)-phenylsulfanyl]-benzoic acid benzenesulfonylamide 

Relevant articles and documents

Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of Candidiasis

Fructose-1,6-bisphosphate aldolase (FBA) represents an attractive new antifungal target. Here, we employed a structure-based optimization strategy to discover a novel covalent binding site (C292 site) and the first-in-class covalent allosteric inhibitors