17931-11-2

Basic information

• Product Name: 5-methyl-4-(4-nitrophenyl)-2-phenylthiazole
• CAS NO: 17931-11-2
• Molecular Weight: 296.349
• Mol File: 17931-11-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-4-(4-nitrophenyl)-2-phenylthiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-4-(4-nitrophenyl)-2-phenylthiazole(17931-11-2)
• EPA Substance Registry System: 5-methyl-4-(4-nitrophenyl)-2-phenylthiazole(17931-11-2)

Safety Data

• Hazardous Substances Data: 17931-11-2(Hazardous Substances Data)

Upstream product

• 25798-60-1 (1-nitro-4-(prop-1-en-1-yl)benzene) 
• 1205-56-7 2-bromo-1-(4-nitrophenyl)propan-1-one 
• 2227-79-4 benzenecarbothioamide 

Downstream Products

• 25021-78-7 4-(5-methyl-2-phenyl-thiazol-4-yl)-aniline 
• 25020-81-9 1,3-bis-[4-(5-methyl-2-phenyl-thiazol-4-yl)-phenyl]-thiourea 

Relevant articles and documents

One pot synthesis of substituted imidazopyridines and thiazoles from styrenes in water assisted by NBS

Heating of commercially available styrenes with NBS in water followed by reaction with 2-aminopyridines or thioamides afforded important heterocyclic scaffolds in a one pot procedure. The reaction proceeds via co-oxidant free, in situ formation of α-bromoketone using NBS as a bromine source as well as an oxidant followed by trapping with suitable nucleophiles to provide imidazopyridines and thiazoles.