179472-31-2

Upstream product

• 55912-20-4 4-chloro-3-nitrobenzyl alcohol 
• 179472-30-1 4-chloro-3-nitrobenzyl hepta-O-acetyl-β-maltoside 

Downstream Products

• 269734-48-7 3-acetamido-4-chlorobenzyl hepta-O-acetyl-β-maltoside 
• 269734-49-8 3-acetamido-4-chlorobenzyl-β-maltoside 
• 721942-70-7 N-{2-Chloro-5-[(2R,3R,4R,5S,6R)-5-((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl]-phenyl}-acetamide 
• 721942-72-9 N-{2-Chloro-5-[(2R,3R,4R,5S,6R)-5-((2R,4aR,6R,7R,8R,8aS)-2-ethyl-7,8-dihydroxy-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl]-phenyl}-acetamide 
• 721942-71-8 N-{2-Chloro-5-[(2R,3R,4R,5S,6R)-5-((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-isopropyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl]-phenyl}-acetamide 
• 721942-76-3 N-{2-Chloro-5-[(2R,3R,4R,5S,6R)-5-((2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-pyridin-4-yl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl]-phenyl}-acetamide 
• 269395-57-5 3-acetamido-4-chlorobenzyl 4',6'-O-benzylidene-β-maltoside 
• 269734-70-5 N-{5-[(2R,3R,4R,5S,6R)-5-((2R,4aR,6R,7R,8R,8aS)-2-Benzyl-7,8-dihydroxy-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl]-2-chloro-phenyl}-acetamide 
• 721942-73-0 N-(2-Chloro-5-{(2R,3R,4R,5S,6R)-5-[(2R,4aR,6R,7R,8R,8aS)-2-(4-chloro-phenyl)-7,8-dihydroxy-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy]-3,4-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxymethyl}-phenyl)-acetamide 
• 269735-41-3 N-{2-chloro-5-[(2,2',3,3',4',6,6')-hepta-O-acetyl-β-D-maltosyloxymethyl]-phenyl}-(9H-fluoren-9-ylmethoxycarbonyl)-L-alaninamide 
• 272437-39-5 N'-{5-[(hepta-O-acetyl-β-D-maltosyloxy)methyl]-2-chlorophenyl}-N-(9H-fluoren-9-ylmethyloxycarbonyl)-L-aspartamide-4-tert-butyl ester 

Relevant academic research and scientific papers

Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation

This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure wherein R1, R2, R3, R4, and R5 are each, independently, hydrogen, acyl of 2-7 carbon atoms, haloac

Stability studies of C-4′,6′ acetal benzylmaltosides synthesized as inhibitors of smooth muscle cell proliferation

In our investigations to synthesize inhibitors of smooth muscle cell (SMC) proliferation, compound 6a displayed submicromolar activity in in vitro antiproliferative assays and reduced intimal thickening using a rat balloon angioplasty model via iv administration. In order to identify analogs that could be administered orally, the chemical instability of the C-4′,6′ acetal of compound 6a was addressed. Several novel variants with increased acid stability and comparable in vitro activity were prepared.

Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation

This invention provides smooth muscle cell proliferation inhibitors of formula I having the structure with the variables defined herein.