17957-64-1Relevant articles and documents
Multicatalytic approach to one-pot stereoselective synthesis of secondary benzylic alcohols
Casnati, Alessandra,Lichosyt, Dawid,Lainer, Bruno,Veth, Lukas,Dydio, Pawe?
supporting information, p. 3502 - 3506 (2021/05/10)
One-pot procedures bear the potential to rapidly build up molecular complexity without isolation and purification of consecutive intermediates. Here, we report multicatalytic protocols that convert alkenes, unsaturated aliphatic alcohols, and aryl boronic acids into secondary benzylic alcohols with high stereoselectivities (typically >95:5 er) under sequential catalysis that integrates alkene cross-metathesis, isomerization, and nucleophilic addition. Prochiral allylic alcohols can be converted to any stereoisomer of the product with high stereoselectivity (>98:2 er, >20:1 dr).
Trimethylsilylazide: A Highly Reactive Silylating Agent for Primary and Secondary Alcohols
Sinou, D.,Emziane, M.
, p. 1045 - 1046 (2007/10/02)
Trimethylsilylazide reacts very rapidly with primary and secondary alcohols at room temperature to give high yields of trimethylsilyl ethers.
