179727-62-9Relevant articles and documents
Use of pentafluorophenyl esters for one-pot protection/activation of amino and thiol carboxylic acids
Gayo, Leah M.,Suto, Mark J.
, p. 4915 - 4918 (2007/10/03)
As part of our efforts in the area of combinatorial chemistry, we have been exploring new methods for the construction of combinatorial libraries in a bidirectional fashion. Herein, we describe a new one-pot procedure for the simultaneous protection/activation of amino and thiol carboxylic acids using pentafluorophenyl trifluoroacetate (TFAPfp) and related pentafluorophenyl reagents (FmocPfp and AcPfp).