179748-04-0

Basic information

• Product Name: 2-BENZYL-5-CYANOINDOLE
• Synonyms: 2-BENZYL-5-CYANOINDOLE;1H-Indole-5-carbonitrile, 2-(phenylMethyl)-;2-benzyl-1H-indole-5-carbonitrile;2-(phenylmethyl)-1H-Indole-5-carbonitrile
• CAS NO: 179748-04-0
• Molecular Formula: C₁₆H₁₂N₂
• Molecular Weight: 232.28
• Mol File: 179748-04-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BENZYL-5-CYANOINDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-5-CYANOINDOLE(179748-04-0)
• EPA Substance Registry System: 2-BENZYL-5-CYANOINDOLE(179748-04-0)

Safety Data

• Hazardous Substances Data: 179748-04-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Benzyl-5-cyanoindole is used as a building block for the synthesis of various pharmaceuticals due to its unique structure and reactivity, which allows for the creation of complex organic molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Benzyl-5-cyanoindole is utilized as a precursor in the development of new compounds with pesticidal or herbicidal properties, leveraging its versatility in organic synthesis to create effective and novel agrochemicals.
Used in Organic Synthesis Research:
2-Benzyl-5-cyanoindole is employed as a key intermediate in organic synthesis research, where its reactivity and structural features are explored to develop new synthetic pathways and methodologies for the formation of complex organic molecules.
Used in Drug Discovery:
As a compound of interest to researchers studying natural products, 2-Benzyl-5-cyanoindole is used in drug discovery efforts to identify and develop new therapeutic agents with potential applications in medicine.
Used in Fine Chemicals Production:
In the production of fine chemicals, 2-Benzyl-5-cyanoindole serves as an essential component, contributing to the synthesis of high-value specialty chemicals used in various industries, including fragrances, dyes, and advanced materials.

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 
• 100-39-0 benzyl bromide 
• 144340-21-6 1-benzenesulfonyl-1H-indole-5-carbonitrile 
• 179748-00-6 2-benzyl-1-(phenylsulfonyl)-1H-indole-5-carbonitrile 

Downstream Products

• 1206725-52-1 3-(2-benzyl-1H-indol-5-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid 
• 1206726-41-1 methyl 3-(2-benzyl-1H-indol-5-yl)-2-(2,2,2-trifluoroethoxy)propanoate 
• 1206726-36-4 (E)-ethyl 3-(2-benzyl-1H-indol-5-yl)-2-(2,2,2-trifluoroethoxy)acrylate 
• 1206726-31-9 (Z)-ethyl 3-(2-benzyl-1H-indol-5-yl)-2-(2,2,2-trifluoroethoxy)acrylate 
• 1206725-47-4 3-(2-benzyl-1H-indol-5-yl)-2-ethoxy-propanoic acid 
• 1206726-26-2 methyl 3-(2-benzyl-1H-indol-5-yl)-2-ethoxypropanoate 
• 182187-43-5 2-benzyl-1H-indole-5-carbaldehyde 

Relevant articles and documents

Synthesis of novel PPARα/γ dual agonists as potential drugs for the treatment of the metabolic syndrome and diabetes type II designed using a new de novo design program PROTOBUILD

Peroxisome proliferator activated receptors (PPARs) have been shown to have critical roles in fatty acid oxidation, triglyceride synthesis, and lipid metabolism - making them an important target in drug discovery. Here we describe the in silico design, sy

Rapid and general protocol towards catalyst-free friedel-crafts C-alkylation of indoles in water assisted by microwave irradiation

An efficient and simplified protocol for uncatalyzed FriedelCrafts alkylation of indoles using microwave irradiation in water is described. A series of functionalized indole derivatives has been synthesized in very short times with moderate to good yields. The combination of microwave irradiation and superheated water offers significant advantages over conventional methods, such as higher selectivities, simplicity, shorter reaction times, and no need for a catalyst.

INDOLE COMPOUNDS

Novel indole compounds which interact with peroxisome proliferator-activated receptors (PPARs) are disclosed. The compounds have an influence on metabolic diseases, obesity and diabetes.

Derivatives of 5-amidine indole as inhibitors of thrombin catalytic activity

Substituted 5-amidine indoles were constructed based upon a computational analysis of putative modes of binding to thrombin utilizing coordinates from the crystal structure of BMS-183,507-α-thrombin complex. These analogs display competitive kinetics for