179811-83-7Relevant academic research and scientific papers
NOVEL BIARYL AMIDE DERIVATIVE
-
Paragraph 0370, (2017/07/31)
PROBLEM TO BE SOLVED: To provide a compound having PDE2A selective inhibitory action, and a pharmaceutical composition comprising the same. SOLUTION: This invention relates to compounds represented by general formula (I) [where p is an integer of 0-6; q is an integer of 1-5; X1 is C-H, N, or O; X2 is N or N-R4b; X3 is N-R4a, C-R4b, or C-H; ring A is a monocyclic heteroaryl ring and the like; ring Q is a benzene ring and the like; R1, R2a, R2b, and R3 are an alkyl group and the like] or their pharmaceutically acceptable salts, or their solvates, and pharmaceutical compositions comprising them. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
GLYT1 TRANSPORTER INHIBITORS AND USES THEREOF IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS
-
Page/Page column 39, (2008/12/07)
Compounds of formula (I) or a salt thereof are provided wherein R1, R2, R6, R7, R8, R9 and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture
COMPOUNDS WHICH INHIBIT THE GLYCINE TRANSPORTER AND USES THEREOF
-
Page/Page column 36-37, (2008/06/13)
Compounds of formula (I) and salts and solvates thereof are provided: wherein R1 to R8 and n are defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
1-(2-ARYL-2-OXOETHYL)-3-PHENYL-1, 4-DIAZASPIRO [4.5]DEC-3-EN-2-ONE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS
-
Page/Page column 35-36, (2008/06/13)
Novel acetophenone compounds of formula (I), compositions containing (I), processes for the preparation of (I), and use of (I) as inhibitors of the glycine transporter, are provided. Definitions of Ar, R5, R6, R7, R8
