179898-72-7

Basic information

• Product Name: 3,3-DIMETHYL-6-NITROINDOLINE
• Synonyms: 3,3-DIMETHYL-6-NITROINDOLINE;3,3-diMethyl-6-nitroindoline 179898-72-7;3,3-DiMethyl-6-nitroindol...;3,3-dimethyl-6-nitro-2,3-dihydro-1H-indole
• CAS NO: 179898-72-7
• Molecular Formula: C10H12N2O2
• Molecular Weight: 192.22
• Mol File: 179898-72-7.mol
• Article Data: 18

Chemical Properties

• Boiling Point: 301.731 °C at 760 mmHg
• Flash Point: 136.282 °C
• Appearance: /
• Density: 1.166 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,3-DIMETHYL-6-NITROINDOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-DIMETHYL-6-NITROINDOLINE(179898-72-7)
• EPA Substance Registry System: 3,3-DIMETHYL-6-NITROINDOLINE(179898-72-7)

Safety Data

• Hazardous Substances Data: 179898-72-7(Hazardous Substances Data)

Usage

General Description

3,3-Dimethyl-6-nitroindoline is a chemical compound that comes under the category of Indolines. 3,3-DIMETHYL-6-NITROINDOLINE carries a systematic IUPAC name of 3,3-dimethyl-2,3-dihydro-1H-indol-6-yl nitrate. Characterized by the presence of nitro groups and methyl groups, 3,3-dimethyl-6-nitroindoline exhibits specific properties that make it suitable for a range of applications. The exact features, including the molecular structure, weight and chemical behaviours, of this compound vary depending upon its chemical environment. Despite its potential uses across several industries, handling of 3,3-dimethyl-6-nitroindoline requires a meticulous approach due to the potential hazards associated with it.

Upstream product

• 100510-64-3 1,3-Dihydro-3,3-dimethyl-6-nitro-2H-indol-2-one 
• 1914-02-9 3,3-dimethylindoline 
• 179898-71-6 2-bromo-N-(2-methyl-2-propenyl)-5-nitroaniline 
• 453562-68-0 1-(3,3-dimethyl-6-nitro-2,3-dihydro-indol-1-yl)-ethanone 
• 207122-91-6 (2-Bromo-phenyl)-(2-methyl-allyl)-amine 
• 615-36-1 2-bromoaniline 

Downstream Products

• 453562-68-0 1-(3,3-dimethyl-6-nitro-2,3-dihydro-indol-1-yl)-ethanone 
• 545393-67-7 1,3,3-trimethylindoline-6-ylamine 
• 179898-73-8 6-amino-3,3-dimethylindoline 

Relevant articles and documents

IMPROVED METHOD FOR THE PREPARATION OF 1-ACETYL-6-AMINO-3,3-DIMETHYL-2,3-DIHYDROINDOLE

The present invention relates to processes for preparing indoline derivatives, particularly 1-acetyl-6-amino-3,3-dimethyl-2,3-dihydroindole.

SUBSTITUTED ARYL-AMINE DERIVATIVES AND METHODS OF USE

The present invention provides classes of compounds, including-their pharmaceutically acceptable derivatives, useful for treating angiogenesis and related diseases such as cancer. Formula I and II wherein R is a 9- or 10-membered heterocyclyl ring selected from 7-isoquinolinyl,..2-methyl-3-oxo-2,3-dihydroindazol-6-yl, [1,6]-naphthydrin-3-yl, [1,7]-naphthydrin-2-yl, 1-oxo-2,3-dihydrobenzofuran-4-yl, 3-oxo-2,3-dihydrobenzofuran-5-yl, dihydro-benzodioxinyl, 6-quinazolinyl, 2-amino-6-quinazolinyl, 4-methylamino-6-quinazolinyl, 2,4-diamino-6 quinazolinyl, 3-oxo-3,4-dihydro-1,4-benzoxazin-6-yl, 2,2-difluoro-l;3-benzodioxol-5-yl and 2,2,3,3 tetrafluoro-2,3-dihydro-l,4-benzodioxin-6-yl, each of which is optionally substituted with one or more substituents selected from halo, haloakyl, C1-6 alkyl, C2-8 alkenyl, C2-8 alkynyl, N-dimethylamino-C1-6-alkyl, N-dimethylamino-C1-6-alkoxy, amino, alkyl-carbonylamino, morpholino-sulfonyl, amino-sulfonyl, oxazolyl, pyrrolyl,4 morpholinyl, carboxyl, cyano, and acetyl; wherein R1 in formula I is selected from unsubstituted or substituted phenyl, 5-6 membered heteroaryl, 9-10 membered bicyclic heterocyclyl and 11-14 membered tricyclic heterocyclyl, and R1 in formula II is selected from specific bicyclic heterocycles.

SUBSTITUTED ALKYLAMINE DERIVATIVES AND METHODS OF USE

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