179929-35-2Relevant academic research and scientific papers
New neplanocin analogues. V. A potent adenosylhomocysteine hydrolase inhibitor lacking antiviral activity. Synthesis and antiviral activity of 6′-carboxylic acid derivatives of neplanocin A
Obara, Takumi,Shuto, Satoshi,Saito, Yasuyoshi,Toriya, Minoru,Ogawa, Kiyoshi,Yaginuma, Satoshi,Shigeta, Shiro,Matsuda, Akira
, p. 1157 - 1167 (2007/10/03)
The 6′-carboxylic acid derivative of neplanocin A 3 was synthesized from NPA, and was converted to the corresponding methyl ester 4 and amides 5 and 6. These were evaluated for their anti-RNA-virus activities. Of the derivatives synthesized, only 5 was ac
