179984-27-1

Basic information

• Product Name: N-{6-[2-(2-Iodo-phenoxymethyl)-allyloxy]-hexyl}-N-prop-2-ynyl-benzenesulfonamide
• Synonyms: N-{6-[2-(2-Iodo-phenoxymethyl)-allyloxy]-hexyl}-N-prop-2-ynyl-benzenesulfonamide
• CAS NO: 179984-27-1
• Molecular Weight: 567.488
• Mol File: 179984-27-1.mol

Chemical Properties

• CAS DataBase Reference: N-{6-[2-(2-Iodo-phenoxymethyl)-allyloxy]-hexyl}-N-prop-2-ynyl-benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{6-[2-(2-Iodo-phenoxymethyl)-allyloxy]-hexyl}-N-prop-2-ynyl-benzenesulfonamide(179984-27-1)
• EPA Substance Registry System: N-{6-[2-(2-Iodo-phenoxymethyl)-allyloxy]-hexyl}-N-prop-2-ynyl-benzenesulfonamide(179984-27-1)

Safety Data

• Hazardous Substances Data: 179984-27-1(Hazardous Substances Data)

Upstream product

• 179984-25-9 1-(2-Chloromethyl-allyloxy)-2-iodo-benzene 
• 629-11-8 1,6-hexanediol 
• 13630-91-6 N-propargyl benzenesulfonamide 

Relevant articles and documents

Palladium catalysed cascade hydrostannylation-bis-cyclisation- intramolecular anion capture. Routes to bridged- and spiro-cyclic small and macrocyclic heterocycles

Palladium catalysed cascade hydrostannylation of terminal alkynes in α,ω-enynes at 0-25°C followed by bis-cyclisation initialed by insertion of Pd(0) into an aryl iodide at 100-110°C and terminating in an intramolecular Stille coupling provides a wide ran

Palladium catalysed tandem cyclisation-anion capture. Part 5: Cascade hydrostannylation-bis-cyclisation-intramolecular anion capture. Synthesis of bridged- and spiro-cyclic small and macrocyclic heterocycles

A series of O- and N-α,ω-enyne derivatives of 2-iodoarylethers and 2-iodoarylamides undergo palladium catalysed cascade hydrostannylation of the ω-alkyne moiety at 0-25°C followed by bis-cyclisation at 100-110°C terminating in intramolecular sp3-sp2 Stille coupling. These cascades provide a wide range of 5/6 and 5/12-17 membered bicyclic spiro- and bridged-ring heterocycles. (C) 2000 Elsevier Science Ltd.