180140-06-1

Upstream product

• 26772-93-0 N-(4-chlorophenyl)-N-methylformamide 
• 79-37-8 oxalyl dichloride 

Relevant academic research and scientific papers

The surprising nucleophilic addition of aminochlorocarbenes to diethyl acetylenedicarboxylate and to oxalyl chloride: Quinolines and benzo[1,4]diazepines from N-alkylformanilides and oxalyl chloride in the presence of Huenig's base

Vilsmeier reagents derived from N-methylformanilides undergo ready deprotonation with Huenig's base. In xylene, the derived nucleophilic arylaminochlorocarbenes bearing 4-methyl- and 4-methoxy-substituents react with acetylenedicarboxylates to give 2-(2-c

Synthetic applications of aminochlorocarbenes: A two-step conversion of N-methylformanilides into 3-arylamino-2-chloroindoles

The thermal cyclisation of 1,2-diarylamino-1,2-dichloroethenes (dimers of arylaminochlorocarbenes) in DMF affords 3-arylamino-2-chloroindoles in good yields (70-91%).