180205-43-0

Basic information

• Product Name: 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid
• Synonyms: 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid
• CAS NO: 180205-43-0
• Molecular Weight: 278.305
• Mol File: 180205-43-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid(180205-43-0)
• EPA Substance Registry System: 3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid(180205-43-0)

Safety Data

• Hazardous Substances Data: 180205-43-0(Hazardous Substances Data)

Upstream product

• 105-53-3 diethyl malonate 
• 54307-67-4 1-bromo-2-benzyloxy-3-chloropropane 
• 54166-15-3 diethyl 3-(benzyloxy)cyclobutane-1,1-dicarboxylate 

Downstream Products

• 1616599-83-7 N-(3-chloro-2-fluorobenzyl)-2’-ethyl-9’-hydroxy-trans-3-methoxy-1‘,8’-dioxo-1‘,2’,4’,8’-tetrahydrospiro[cyclobutane-1,3’-pyrido[1,2-a]pyrazine]-7’-carboxamide 
• 180205-44-1 ethyl 3-phenylmethyloxy-1-carbamoyl-1-cyclobutylcarboxylate 
• 140480-88-2 (+/-)-1-amino-3-(phosphonomethylene)cyclobutanecarboxylic acid 
• 413597-67-8 ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-hydroxycyclobutane-1-carboxylate 
• 129287-91-8 ethyl 1-<<(tert-butyloxy)carbonyl>amino>-3-oxocyclobutane-1-carboxylate 
• 413597-66-7 ethyl 3-(benzyloxy)-1-<<(tert-butyloxy)carbonyl>amino>cyclobutane-1-carboxylate 

Relevant articles and documents

SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR

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Diastereoselective synthesis of hydantoin- and isoxazoline-substituted dispirocyclobutanoids

Synthetic strategies for constructing novel achiral cyclobutanoid isoxazolidinoimidazolidinedione heterocycles, with a generalized structure of II, have been developed via 1,3-dipolar cycloaddition and carbanilide cyclization transformations from methylenecyclobutane 13. The exo methylene cyclobutane system has made the realization of some diasteroselectivity possible, such that the H-bond (Boc-NH) directed product (i.e., 14) was obtained with 3:1 selectivity relative to the non-H-bond directed product (i.e., 15).