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3-(benzyloxy)-1-carbethoxycyclobutane-1-carboxylic acid is a complex organic compound with the molecular formula C17H18O5. It features a cyclobutane ring, which is a four-membered carbon ring, with a carbethoxy group (ester of carboxylic acid) and a benzyloxy group attached to it. The carbethoxy group is an ester derived from acetic acid, while the benzyloxy group is a benzyl ether. This chemical is primarily used in the synthesis of various pharmaceuticals and biologically active compounds due to its unique structure and reactivity. It is an important intermediate in organic chemistry, particularly in the preparation of cyclobutane derivatives with potential applications in drug development and material science.

180205-43-0

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180205-43-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 180205-43-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,2,0 and 5 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 180205-43:
(8*1)+(7*8)+(6*0)+(5*2)+(4*0)+(3*5)+(2*4)+(1*3)=100
100 % 10 = 0
So 180205-43-0 is a valid CAS Registry Number.

180205-43-0Relevant academic research and scientific papers

SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND PHARMACEUTICAL USE OF SAME AS HIV INTEGRASE INHIBITOR

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Paragraph 1360-1366; 1468-1474, (2014/08/19)

Provided is a substituted spiropyrido[1,2-a]pyrazine derivative or a pharmaceutically acceptable salt thereof, which is useful as an anti-HIV agent. The present invention relates to a compound represented by the following formula [I] or [II] or a pharmace

Diastereoselective synthesis of hydantoin- and isoxazoline-substituted dispirocyclobutanoids

Park, Kyung-Ho,Kurth, Mark J.

, p. 3520 - 3524 (2007/10/03)

Synthetic strategies for constructing novel achiral cyclobutanoid isoxazolidinoimidazolidinedione heterocycles, with a generalized structure of II, have been developed via 1,3-dipolar cycloaddition and carbanilide cyclization transformations from methylenecyclobutane 13. The exo methylene cyclobutane system has made the realization of some diasteroselectivity possible, such that the H-bond (Boc-NH) directed product (i.e., 14) was obtained with 3:1 selectivity relative to the non-H-bond directed product (i.e., 15).

Pyrimidine compound and anti-rotavirus composition

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, (2008/06/13)

A pyrimidine compound of the formula [I]wherein R1 is H, C1-C4 lower alkyl, halogen atom, -OH, C1-C4 lower alkoxy, C1-C6 hydroxy(lower)alkoxy or -NH2; R2 is H, -NH2 or -NHCOCH3; R3 is -NR5(CH2)i-CH2OH; R4 is H, halogen atom, -NH2, -CN, -CHO, -CH2OH, -COOH

Synthesis and Activity of a Potent N-Methyl-D-aspartic Acid Agonist, trans-1-Aminocyclobutane-1,3-dicarboxylic Acid, and Related Phosphonic and Carboxylic Acids

Allan, Robin D.,Hanrahan, Jane R.,Hambley, Trevor W.,Johnston, Graham A. R.,Mewett, Kenneth N.,Mitrovic, Ann D.

, p. 2905 - 2915 (2007/10/02)

We report the synthesis of a series of 3-carboxy-, 3-(carboxymethyl)-, 3-(1o-phosphoalkenyl)-, and 3-(1o-phosphonoalkyl)-1-aminocyclobutane-1-carboxylic acids for evaluation as agonists or antagonists of neurotransmission at excitatory amino acid receptor

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