
Tetrahedron Letters p. 5065 - 5068 (1996)
Update date:2022-07-30
Topics:
Kukkola, Paivi J.
Bilci, Natalie A.
Ikeler, Theodore J.
The described synthesis of isomeric isoindoline dicarboxylic acid analogs 1 and 2, two potent ETA selective receptor antagonists, involves an efficient regioselective route to highly functionalized dibenzoylbenzenes and a novel methodology for the stereoselective preparation of trans and cis 1,3- disubstituted isoindolines.
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