180311-17-5

Basic information

• Product Name: Benzoic acid 2'-(2-benzoylamino-propionyloxy)-[1,1']binaphthalenyl-2-yl ester
• Synonyms: Benzoic acid 2'-(2-benzoylamino-propionyloxy)-[1,1']binaphthalenyl-2-yl ester
• CAS NO: 180311-17-5
• Molecular Weight: 565.625
• Mol File: 180311-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid 2'-(2-benzoylamino-propionyloxy)-[1,1']binaphthalenyl-2-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid 2'-(2-benzoylamino-propionyloxy)-[1,1']binaphthalenyl-2-yl ester(180311-17-5)
• EPA Substance Registry System: Benzoic acid 2'-(2-benzoylamino-propionyloxy)-[1,1']binaphthalenyl-2-yl ester(180311-17-5)

Safety Data

• Hazardous Substances Data: 180311-17-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 180311-13-1 tert-Butoxycarbonylamino-acetic acid 2'-hydroxy-[1,1']binaphthalenyl-2-yl ester 
• 180311-15-3 (Benzhydrylidene-amino)-acetic acid 2'-hydroxy-[1,1']binaphthalenyl-2-yl ester 
• 180311-16-4 2-(Benzhydrylidene-amino)-propionic acid 2'-hydroxy-[1,1']binaphthalenyl-2-yl ester 
• 602-09-5 1,1'-bi-2-naphthol 

Downstream Products

• 7244-67-9 N-benzoyl-L-alanine methyl ester 
• 7260-27-7 (R)-N-benzoylalanine methyl ester 
• 17966-60-8 D-N-benzoylalanine 
• 2198-64-3 N-benzoyl-L-alanine 

Relevant articles and documents

Asymmetric synthesis of uncommon α-amino acids by diastereoselective alkylations of a chiral glycine equivalent

For the purpose of practical preparations of a variety of enantiomerically pure uncommon α-amino acids, alkylations of the chiral glycine equivalent 5, which possesses axially chiral binaphthol as an auxiliary, with several electrophiles were investigated. The alkylation proceeded smoothly in satisfactory chemical yield with high diastereo-selectivities to give protected α-amino acid derivatives. The free hydroxyl group of the auxiliary played an important role for the induction of diastereoselectivity. Using (S)-1,1'-binaphthalene-2,2'-diol as a chiral auxiliary, D-α-amino acid derivatives having the unnatural (R)-configuration were predominantly obtained. Some of the alkylated products were converted into free non- proteinogenic D-α-amino acids.