180322-86-5 Usage
Description
(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID is a chiral amino acid derivative featuring a cyclopropane ring, a carboxylic acid group, and an N-BOC (tert-butyloxycarbonyl) protected amino group. (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID is of interest to synthetic and medicinal chemists due to its unique structure and functional groups, and it holds potential for applications in organic synthesis and the development of bioactive molecules.
Uses
Used in Organic Synthesis:
(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID is used as a key intermediate in the synthesis of complex organic molecules, particularly in the creation of peptidomimetics and other bioactive compounds. Its unique cyclopropane ring and protected amino group facilitate the development of novel chemical entities with potential applications in various fields.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID is utilized as a building block for the design and synthesis of new drugs. Ongoing studies are exploring its biological activity and potential as a therapeutic agent, with the aim of discovering its effects on various biological targets and its suitability for treating specific diseases.
Used in Medicinal Chemistry:
(1R,2R)-N-BOC-1-AMINO-2-PHENYLCYCLOPROPANECARBOXYLIC ACID is employed as a versatile component in medicinal chemistry for the development of innovative drug candidates. Its chiral center and functional groups allow for the fine-tuning of molecular properties, which can lead to the optimization of drug efficacy, selectivity, and pharmacokinetics.
Check Digit Verification of cas no
The CAS Registry Mumber 180322-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,3,2 and 2 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 180322-86:
(8*1)+(7*8)+(6*0)+(5*3)+(4*2)+(3*2)+(2*8)+(1*6)=115
115 % 10 = 5
So 180322-86-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H19NO4/c1-14(2,3)20-13(19)16-15(12(17)18)9-11(15)10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,16,19)(H,17,18)/p-1/t11-,15-/m1/s1
180322-86-5Relevant articles and documents
Asymmetric cyclopropanations by rhodium(II) N-(arylsulfonyl)prolinate catalyzed decomposition of vinyldiazomethanes in the presence of alkenes. Practical enantioselective synthesis of the four stereoisomers of 2-phenylcyclopropan-1-amino acid
Davies, Huw M. L.,Bruzinski, Paul R.,Lake, Debra H.,Kong, Norman,Fall, Michael J.
, p. 6897 - 6907 (2007/10/03)
The rhodium N-(arylsulfonyl)prolinate catalyzed decomposition of vinyldiazomethanes in the presence of alkenes leads to a very general method for the synthesis of functionalized cyclopropanes in a highly diastereoselective and enantioselective mode. A det
