1805-77-2

Usage

Chemical class

Benzofurochromenones

Explanation

1,3,8,9-tetramethoxy-6H-[1]benzofuro[3,2-c]chromen-6-one belongs to a class of organic compounds that have a benzene ring fused with a furan ring and a chromenone moiety.

Explanation

The molecule has a complex structure with multiple functional groups and a fused ring system.

Explanation

Studies have shown that 1,3,8,9-tetramethoxy-6H-[1]benzofuro[3,2-c]chromen-6-one has potential pharmacological properties, including the ability to act as an antioxidant and reduce inflammation.

Explanation

Due to its unique structure and properties, 1,3,8,9-tetramethoxy-6H-[1]benzofuro[3,2-c]chromen-6-one has potential applications in the field of drug discovery and development, particularly in the search for new therapeutic agents.

Explanation

The unique structure and properties of 1,3,8,9-tetramethoxy-6H-[1]benzofuro[3,2-c]chromen-6-one make it a subject of interest for scientists and researchers to further study and explore its potential applications and properties.

Molecular structure

Complex

Methoxy groups

Four

Pharmacological properties

Antioxidant and anti-inflammatory effects

Applications

Drug discovery and development

Research interest

Further research and exploration

Upstream product

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• 1432504-85-2 5,7-dimethoxy-4-(methylthio)-2H-chromen-2-one 
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• 38444-50-7 2,4,5-trimethoxybenzeneacetonitrile 
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Relevant academic research and scientific papers

Copper-catalyzed intramolecular cross dehydrogenative coupling approach to coumestans from 2′-hydroxyl-3-arylcoumarins

A copper-catalyzed intramolecular cross dehydrogenative C-O coupling reaction of 2′-hydroxyl-3-arylcoumarins was developed. This protocol provided a facile and efficient strategy for the construction of natural coumestans and derivatives in moderate to high yields. This transformation exhibited good functional group compatibility and was amenable to substrates with free phenolic hydroxyl groups.

Tin tetrachloride-catalyzed regiospecific allylic substitution of quinone monoketals: An easy entry to benzofurans and coumestans

A highly regioselective allylic substitution of quinone monoketals with a-oxoketene dithioacetals is achieved under the catalysis of only tin tetrachloride (1 mol%). The advantages of the reaction, including its simplicity, rapidity, low catalyst loading of inexpensive tin tetrachloride, mild conditions and; in particular, the regiospecificity, is proposed to be due to a pseudo-intramolecular process. This new synthetic method provides a facile [3+2] cycloaddition route to benzofurans and is highlighted by the synthesis of coumestans.

Synthesis of coumestan derivatives via FeCl3-mediated oxidative ring closure of 4-hydroxy coumarins

A concise and efficient approach to the syntheses of coumestan analogues has been developed. The underpinning strategy involves a FeCl 3-mediated direct intramolecular oxidative annellation of 4-hydroxy-3-phenyl-2H-chromen-2-one derivatives. Utilizing this synthetic protocol, a variety of coumestan derivatives were conveniently obtained from readily available reagents.