1806-25-3 Usage
Uses
Used in Research and Development:
2-Fluoro-7-nitrofluorene, 99 is used as a research reagent for its fluorescent properties, facilitating studies in organic synthesis and chemical research. Its strong absorption and emission in the ultraviolet region make it a valuable tool for investigating various chemical processes and reactions.
Used in Fluorescence Microscopy:
In the field of fluorescence microscopy, 2-Fluoro-7-nitrofluorene, 99 serves as a fluorescent dye, enabling the visualization of specific structures or molecules within a sample. Its ultraviolet properties enhance the imaging capabilities, providing detailed and clear microscopic images.
Used in Analytical Chemistry:
2-Fluoro-7-nitrofluorene, 99 is employed as a fluorescent marker in analytical chemistry for detecting and quantifying specific compounds or elements. Its high purity and strong fluorescence make it an effective tool for sensitive and accurate measurements.
Used in Materials Science:
In materials science, 2-Fluoro-7-nitrofluorene, 99 is utilized for the development of new materials with specific optical properties. Its fluorescence characteristics can be integrated into the design of advanced materials for various applications, such as sensors, optical devices, and more.
Used in Pharmaceutical Industry:
2-Fluoro-7-nitrofluorene, 99 is used as a fluorescent probe in the pharmaceutical industry for drug discovery and development. Its ability to bind and fluoresce in the presence of specific biological targets aids in the identification of potential drug candidates and the study of their interactions with biological systems.
Used in Environmental Science:
In environmental science, 2-Fluoro-7-nitrofluorene, 99 is applied as a tracer for monitoring the behavior and distribution of pollutants in the environment. Its fluorescent properties allow for the tracking and analysis of contaminants, contributing to environmental protection and remediation efforts.
Check Digit Verification of cas no
The CAS Registry Mumber 1806-25-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,0 and 6 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1806-25:
(6*1)+(5*8)+(4*0)+(3*6)+(2*2)+(1*5)=73
73 % 10 = 3
So 1806-25-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H8FNO2/c14-10-1-3-12-8(6-10)5-9-7-11(15(16)17)2-4-13(9)12/h1-4,6-7H,5H2
1806-25-3Relevant academic research and scientific papers
NOVEL ASPARTYLAMIDE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTERS
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Page/Page column 31, (2013/09/26)
The compounds of the invention are inhibitors of excitatory amino acid transporters (EAAT) that penetrate the blood-brain barrier to access the central nervous system. The compounds of the invention follow the structural formula: or a salt, ester or prodr
Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT-2
Greenfield, Alexander,Grosanu, Cristina,Dunlop, John,McIlvain, Beal,Carrick, Tikva,Jow, Brian,Lu, Qiang,Kowal, Dianne,Williams, John,Butera, John
, p. 4985 - 4988 (2007/10/03)
Excitatory amino acid transporters (EAATs) play a pivotal role in maintaining glutamate homeostasis in the mammalian central nervous system, with the EAAT-2 subtype thought to be responsible for the bulk of the glutamate uptake in forebrain regions. A complete elucidation of the functional role of EAAT-2 has been hampered by the lack of potent and selective pharmacological tools. In this study, we describe the synthesis and biological activities of novel aryl-ether, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of EAAT-2. Compound (16) represents one of the most potent (IC50 = 85 ± 5 nM) and selective inhibitors of EAAT-2 identified to date.
