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7-fluoro-9H-fluoren-2-amine is an organic compound with the molecular formula C13H10FN and a molecular weight of 201.22 g/mol. It is a derivative of fluorene, a polycyclic aromatic hydrocarbon, and features a fluorine atom at the 7-position and an amino group at the 2-position. This chemical is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly those containing fluorine atoms, due to its unique reactivity and stability. The compound is known for its potential applications in the development of new drugs and pesticides, as well as in materials science for the creation of novel fluorinated polymers.

363-16-6

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363-16-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 363-16-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 3 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 363-16:
(5*3)+(4*6)+(3*3)+(2*1)+(1*6)=56
56 % 10 = 6
So 363-16-6 is a valid CAS Registry Number.

363-16-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-fluoro-9H-fluoren-2-amine

1.2 Other means of identification

Product number -
Other names 2-Fluor-7-amino-fluoren

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:363-16-6 SDS

363-16-6Relevant academic research and scientific papers

NOVEL ASPARTYLAMIDE INHIBITORS OF EXCITATORY AMINO ACID TRANSPORTERS

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, (2013/09/26)

The compounds of the invention are inhibitors of excitatory amino acid transporters (EAAT) that penetrate the blood-brain barrier to access the central nervous system. The compounds of the invention follow the structural formula: or a salt, ester or prodr

Synthesis and biological activities of aryl-ether-, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of the high-affinity glutamate transporter EAAT-2

Greenfield, Alexander,Grosanu, Cristina,Dunlop, John,McIlvain, Beal,Carrick, Tikva,Jow, Brian,Lu, Qiang,Kowal, Dianne,Williams, John,Butera, John

, p. 4985 - 4988 (2007/10/03)

Excitatory amino acid transporters (EAATs) play a pivotal role in maintaining glutamate homeostasis in the mammalian central nervous system, with the EAAT-2 subtype thought to be responsible for the bulk of the glutamate uptake in forebrain regions. A complete elucidation of the functional role of EAAT-2 has been hampered by the lack of potent and selective pharmacological tools. In this study, we describe the synthesis and biological activities of novel aryl-ether, biaryl-, and fluorene-aspartic acid and diaminopropionic acid analogs as potent inhibitors of EAAT-2. Compound (16) represents one of the most potent (IC50 = 85 ± 5 nM) and selective inhibitors of EAAT-2 identified to date.

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