180606-36-4

Basic information

• Product Name: 2-(4-fluorophenyl)-5-methylpyrimidin-4-one
• Synonyms: 2-(4-fluorophenyl)-5-methylpyrimidin-4-one
• CAS NO: 180606-36-4
• Molecular Weight: 204.204
• Mol File: 180606-36-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-5-methylpyrimidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-5-methylpyrimidin-4-one(180606-36-4)
• EPA Substance Registry System: 2-(4-fluorophenyl)-5-methylpyrimidin-4-one(180606-36-4)

Safety Data

• Hazardous Substances Data: 180606-36-4(Hazardous Substances Data)

Upstream product

• 75-91-2 tert.-butylhydroperoxide 
• 76128-79-5 2-(4-fluorophenyl)pyrimidin-4-one 
• 51673-64-4 methyl 2-methyl-3-oxopropanoate 
• 456-14-4 4-fluorobenzamidine hydrochloride 

Relevant articles and documents

Methyl ketone derivative, and preparation method and applications thereof

The invention discloses a methyl ketone derivative, and a preparation method and applications thereof. The preparation method comprises following steps: a ketone derivative and an organic peroxide are dissolved in a solvent, and reaction is carried out at 80 to 130 DEG C so as to obtain methyl pyrimidone and a methyl pyrimidone derivative. According to the preparation method, the ketone derivative is taken as a starting material; the raw materials are easily and widely available; products of different kinds can be obtained via the preparation method, and can be used directly or used in other further reaction. No metal is involved, so that the preparation method is suitable to be applied in pharmaceutical preparation technology. The preparation method is short in route, mild in reaction conditions, simple in reaction operation and postprocessing process, and high in yield, and is suitable for large-scale production.