180633-71-0

Basic information

• Product Name: (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanone
• Synonyms: (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanone
• CAS NO: 180633-71-0
• Molecular Weight: 667.597
• Mol File: 180633-71-0.mol

Chemical Properties

• CAS DataBase Reference: (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanone(180633-71-0)
• EPA Substance Registry System: (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanone(180633-71-0)

Safety Data

• Hazardous Substances Data: 180633-71-0(Hazardous Substances Data)

Upstream product

• 180633-69-6 (1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-[4-iodo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-methanol 
• 98-09-9 benzenesulfonyl chloride 
• 180633-65-2 6-methoxymethoxy-1H-indole 
• 1038921-43-5 6-methoxymethyloxy-3-iodo-1H-indole 
• 180633-67-4 1-benzenesulfonyl-3-iodo-6-methoxymethoxy-1H-indole 

Downstream Products

• 112515-44-3 Bromotopsentin 
• 1038921-29-7 [4-(1-benzenesulfonyl-6-bromo-1H-indol-3-yl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-imidazol-2-yl]-(1-benzenesulfonyl-6-methoxymethoxy-1H-indol-3-yl)-methanone 

Relevant articles and documents

Convenient access to bis-indole alkaloids. Application to the synthesis of?topsentins

Topsentins and related bis-indole alkaloids may be efficiently synthesized through an addition/oxidation sequence leading to 2-(3-indolylcarbonyl)-imidazole derivatives followed by a Pd-catalyzed heteroarylation with the appropriate 3-stannylindoles.

A three-component coupling approach to the marine bis-indole alkaloids: Topsentin, deoxytopsentin and bromotopsentin

The total syntheses of three marine bis-indole alkaloids (1, 2, 4) of the topsentin family together with the synthesis of unnatural deoxybromotopsentin (33) are described. Key elements include, a 1,2-addition-oxidation sequence to construct the bis-hetero