180692-67-5Relevant academic research and scientific papers
Cyclohexenone construction by intramolecular alkylidene C-H insertion: Synthesis of (+)-cassiol
Taber, Douglass F.,Meagley, Robert P.,Doren, Douglas J.
, p. 5723 - 5728 (2007/10/03)
We report new procedures for stereoselective cyclopentene and cyclohexenone construction employing the alkylidene carbene C-H insertion reaction. Described are diastereoselective insertion into methylene and enantiospecific insertion into methine C-H bonds. The latter case leads directly to the enantioselective synthesis of (+)-cassiol (1).
