18088-97-6

Usage

Uses

Used in Chemical Synthesis:
2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid is used as an intermediate in the synthesis of various organic compounds, particularly in the production of 1,1,5,5-Tetramethyl-2-(1-methylethenyl)cyclohexane (T305630). 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid is essential in the study of synthetic elastomers and natural rubber, where it aids in understanding the formation of cyclic oligomers in the copolymerization of isoprene with isobutylene.
Used in Rubber Industry:
In the rubber industry, 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid plays a crucial role in the development and improvement of synthetic elastomers. Its application contributes to the enhancement of the properties of rubber materials, such as their elasticity, durability, and resistance to various environmental factors.
Used in Pharmaceutical Research:
Although not explicitly mentioned in the provided materials, the unique structure and properties of 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid may also make it a potential candidate for pharmaceutical research. Its chemical properties could be harnessed for the development of new drugs or drug delivery systems, particularly in the field of drug synthesis and modification.

Upstream product

• 70092-25-0 1-(2,4,4-trimethyl-cyclohex-1-enyl)-ethanone 
• 870-63-3 prenyl bromide 
• 638-10-8 ethyl 3-methylbut-2-enoate 
• 855657-56-6 isopropenyl-(3-methyl-but-2-enyl)-malonic acid diethyl ester 
• 503-46-8 1,5,5-trimethylcyclohexene 
• 185248-59-3 2-(Diethoxy-phosphoryloxy)-4,4-dimethyl-cyclohex-1-enecarboxylic acid methyl ester 
• 32767-46-7 methyl 4,4-dimethyl-2-oxocyclohexancarboxylate 
• 2979-19-3 3,3-dimethylcyclohexanone 
• 1845-54-1 (±)-ethyl 5-methyl-2-(prop-1-en-2-yl)hex-4-enoate 
• 64-18-6 formic acid 
• 497-67-6 2-(1-methylethenyl)-5-methyl-4-hexenoic acid 
• 7664-93-9 sulfuric acid 
• 17920-96-6 methyl β-cyclolavandulate 
• 5939-87-7 (2,4,4-trimethyl-1-cyclohexene)carbaldehyde 

Downstream Products

• 103985-40-6 (2,4,4-trimethyl-1-cyclohexen-1-yl)methanol 
• 67451-72-3 1-(bromomethyl)-2,4,4-trimethyl-1-cyclohexene 
• 207505-91-7 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)(9H-carbazol-1-yl)]propan-2-ol 
• 207505-90-6 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 937811-11-5 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylacetyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 5939-87-7 (2,4,4-trimethyl-1-cyclohexene)carbaldehyde 
• 17920-96-6 methyl β-cyclolavandulate 

Relevant academic research and scientific papers

Transition metals in organic synthesis, Part 98.1 Transition metal mediated total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin

An efficient total synthesis of (±)-lavanduquinocin, a potent neuronal cell protecting alkaloid from Streptomyces viridochromogenes, is reported. Key-steps are an iron-mediated one-pot construction of the carbazole framework and a nickel-mediated coupling reaction. ARKAT-USA, Inc.

Transition metal complexes in organic synthesis, Part 42. First total synthesis of the potent neuronal cell protecting substance (±)- lavanduquinocin via iron- and nickel-mediated coupling reactions

The first total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin is described by using an iron-mediated construction of the carbazole skeleton and a nickel-mediated alkylation as the key-steps.

An efficient synthetic method for β-cyclolavandulal and its corresponding alcohol

3,3-Dimethylcyclohexanone (5) was efficiently converted to methyl β-cyclolavandulate (6) in 74% yield in three steps, one of which included the preparation of β-methyl α,β-unsaturated esters by coupling lithium dimethylcuprate with enol phosphates of β-ox

Preparation of organic acids and/or esters

Carboxylic acids and/or esters are prepared by converting the STR1 moiety in a 1-substituted 2,2-trihaloethanol, or derivative wherein X represents halogen and R is hydrogen or an acyl group to an organic acid and/or ester grouping of the formula STR2 wherein R' is hydrogen or alkyl of 1 to 6 carbon atoms, in the process which comprises reacting the 1-substituted 2,2,2-trihaloethanol or acylated derivative with molecular oxygen in the presence of a catalyst comprising a complex of a transition metal having an atomic number from 21-30, 39-48 or 57-80 and at least one molecule of a ligand containing trivalent nitrogen, phosphorus, arsenic or antimony. This reaction is carried out in a reaction medium comprising an alcohol or aqueous alcohol having 1 to 6 carbon atoms optionally containing an alkali metal, said alcoholic solvent also serving as a reactant source when carboxylic acid esters are formed.