18088-97-6

Basic information

• Product Name: 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid
• Synonyms: 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid;β-Cyclolavandulic acid
• CAS NO: 18088-97-6
• Molecular Formula: C₁₀H₁₆O₂
• Molecular Weight: 168.23
• Mol File: 18088-97-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: Room Temperature
• Solubility: Chloroform
• CAS DataBase Reference: 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid(18088-97-6)
• EPA Substance Registry System: 2,4,4-Trimethyl-1-cyclohexene-1-carboxylic acid(18088-97-6)

Safety Data

• Hazardous Substances Data: 18088-97-6(Hazardous Substances Data)

Usage

Uses

β-Cyclolavandulic Acid is a proposed intermediate in the synthesis of 1,1,5,5-Tetramethyl-2-(1-methylethenyl)cyclohexane (T305630), which is analyzed in synthetic elastomers and natural rubber studies of cyclic oligomer formation in the copolymerization of isoprene with isobutylene.

Upstream product

• 870-63-3 prenyl bromide 
• 638-10-8 ethyl 3-methylbut-2-enoate 
• 855657-56-6 isopropenyl-(3-methyl-but-2-enyl)-malonic acid diethyl ester 
• 32767-46-7 methyl 4,4-dimethyl-2-oxocyclohexancarboxylate 
• 2979-19-3 3,3-dimethylcyclohexanone 
• 1845-54-1 (±)-ethyl 5-methyl-2-(prop-1-en-2-yl)hex-4-enoate 
• 64-18-6 formic acid 
• 497-67-6 2-(1-methylethenyl)-5-methyl-4-hexenoic acid 
• 7664-93-9 sulfuric acid 
• 17920-96-6 methyl β-cyclolavandulate 
• 5939-87-7 (2,4,4-trimethyl-1-cyclohexene)carbaldehyde 
• 70092-25-0 1-(2,4,4-trimethyl-cyclohex-1-enyl)-ethanone 
• 503-46-8 1,5,5-trimethylcyclohexene 
• 185248-59-3 2-(Diethoxy-phosphoryloxy)-4,4-dimethyl-cyclohex-1-enecarboxylic acid methyl ester 

Downstream Products

• 937811-11-5 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylacetyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 207505-90-6 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)-9H-carbazol-1-yl]propan-2-yl acetate 
• 5939-87-7 (2,4,4-trimethyl-1-cyclohexene)carbaldehyde 
• 207505-91-7 1-[3,4-dimethoxy-2-methyl-6-(2,4,4-trimethyl-1-cyclohexen-1-ylmethyl)(9H-carbazol-1-yl)]propan-2-ol 
• 67451-72-3 1-(bromomethyl)-2,4,4-trimethyl-1-cyclohexene 
• 17920-96-6 methyl β-cyclolavandulate 
• 103985-40-6 (2,4,4-trimethyl-1-cyclohexen-1-yl)methanol 

Relevant articles and documents

Transition metals in organic synthesis, Part 98.1 Transition metal mediated total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin

An efficient total synthesis of (±)-lavanduquinocin, a potent neuronal cell protecting alkaloid from Streptomyces viridochromogenes, is reported. Key-steps are an iron-mediated one-pot construction of the carbazole framework and a nickel-mediated coupling reaction. ARKAT-USA, Inc.

An efficient synthetic method for β-cyclolavandulal and its corresponding alcohol

3,3-Dimethylcyclohexanone (5) was efficiently converted to methyl β-cyclolavandulate (6) in 74% yield in three steps, one of which included the preparation of β-methyl α,β-unsaturated esters by coupling lithium dimethylcuprate with enol phosphates of β-ox