67451-72-3Relevant academic research and scientific papers
Total Syntheses of Pyocyanin, Lavanducyanin, and Marinocyanins A and B
Kohatsu, Haruki,Kamo, Shogo,Tomoshige, Shusuke,Kuramochi, Kouji
supporting information, p. 7311 - 7314 (2019/10/02)
Total syntheses of pyocyanin, lavanducyanin, and marinocyanins A and B have been accomplished. The N-substituted phenazin-1-one skeleton, a common framework of these natural products, was constructed through the oxidative condensation of pyrogallol with N-substituted benzene-1,2-diamine under an oxygen atmosphere in a single step. Regioselective bromination with N-bromosuccinimide at the C-2 position of N-alkylated phenazin-1-ones afforded brominated natural products.
Transition metals in organic synthesis, Part 98.1 Transition metal mediated total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin
Froehner, Wolfgang,Reddy, Kethiri R.,Knoelker, Hans-Joachim
, p. 330 - 342 (2013/09/24)
An efficient total synthesis of (±)-lavanduquinocin, a potent neuronal cell protecting alkaloid from Streptomyces viridochromogenes, is reported. Key-steps are an iron-mediated one-pot construction of the carbazole framework and a nickel-mediated coupling reaction. ARKAT-USA, Inc.
Transition metal complexes in organic synthesis, Part 42. First total synthesis of the potent neuronal cell protecting substance (±)- lavanduquinocin via iron- and nickel-mediated coupling reactions
Knoelker, Hans-Joachim,Froehner, Wolfgang
, p. 2537 - 2540 (2007/10/03)
The first total synthesis of the potent neuronal cell protecting alkaloid (±)-lavanduquinocin is described by using an iron-mediated construction of the carbazole skeleton and a nickel-mediated alkylation as the key-steps.
