1809-02-5

Usage

Physical state

Colorless liquid

Odor

Strong, sweet

Primary use

Production of synthetic rubbers and plastics

Hazardous substance

Yes

Health effects

Respiratory irritation, dizziness, headaches

Carcinogenic potential

Potential human carcinogen

Cancer risk

Increased risk of lung cancer with long-term exposure

Industrial regulations

Strict handling and use regulations to minimize exposure to workers and the environment

Upstream product

• 71600-39-0 1,1-dibromo-2-chloromethyl-2-methylcyclopropane 
• 78-80-8 2-methylbut-1-en-3-yne 

Downstream Products

• 76392-10-4 4-chloro-1,3-dimethyl-cyclohex-3-enecarboxylic acid methyl ester 
• 108541-54-4 4-chloro-5-methyl-cyclohexa-1,4-diene-1,2-dicarboxylic acid dimethyl ester 
• 91058-85-4 4,4,5,5-Tetracyan-1-chlor-2-methyl-cyclohexen 
• 600-22-6 pyruvic acid methyl ester 
• 109-87-5 Dimethoxymethane 
• 79-20-9 acetic acid methyl ester 
• 10076-48-9 methyl 2,2-dimethoxypropionate 
• 80-62-6 methacrylic acid methyl ester 
• 108365-85-1 2-Chlor-3,3-dimethoxy-1-buten 
• 72014-09-6 3-methyl-1-phenylpenta-3,4-dien-1-ol 
• 872-93-5 3-methylsulfolane 

Relevant academic research and scientific papers

A SIMPLE ROUTE TO 1-BROMOBICYCLOBUTANES BY INTRAMOLECULAR TRAPPING OF 1-BROMO-1-LITHIOCYCLOPROPANES

Reaction of the dibromides (5) and (10) with methyl lithium in ether leads to products derived by 1,3-dehalogenation, (6) and (11), whereas (15) and (16) undergo 1,1-dehalogenation and rearrangement to allenes, (17) and (18).

Reactions of 3-Chloro-3-methyl-1-butyne with Hydrogen Chloride: Evidence Against an Electrophilic Addition Reaction

Reactions of 3-chloro-3-methyl-1-butyne (1) with an excess of anhydrous hydrogen chloride in the liquid phase afforded approx. 16 products.Major product was 1,1,3-trichloro-3-methylbutane (6).In addition, (E)-1,3-dichloro-3-methyl-1-butene (5) and (Z)- and (E)-1,3-dichloro-2-methyl-2-butene (11a, b) were formed in considerable amounts.The expected products of an electrophilic addition to the triple bond, however, were only found in very minute amounts.The formation of the products obtained was rationalized by heterolysis of the C-Cl bond in the substrate 1 and subsequent reactions of the ensuing intermediate mesomeric cation A.