180959-10-8

Basic information

• Product Name: (S)-1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(2-methylsulfanyl-quinazolin-4-ylamino)-propan-2-ol
• Synonyms: (S)-1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(2-methylsulfanyl-quinazolin-4-ylamino)-propan-2-ol
• CAS NO: 180959-10-8
• Molecular Weight: 439.582
• Mol File: 180959-10-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(2-methylsulfanyl-quinazolin-4-ylamino)-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(2-methylsulfanyl-quinazolin-4-ylamino)-propan-2-ol(180959-10-8)
• EPA Substance Registry System: (S)-1-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-3-(2-methylsulfanyl-quinazolin-4-ylamino)-propan-2-ol(180959-10-8)

Safety Data

• Hazardous Substances Data: 180959-10-8(Hazardous Substances Data)

Upstream product

• 58803-74-0 4-chloro-2-(methylthio)quinazoline 
• 180959-08-4 (S)-(+)-1-amino-3-(4-(2-methoxyphenyl)piperazin-1-yl)propan-2-ol 
• 180959-06-2 (R)-(+)-1-phthaloylamino-3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-2-ol 
• 35386-24-4 1-(2-Methoxyphenyl)piperazine 
• 54855-81-1 2-methylthioquinazolin-4(3H)-one 
• 13906-09-7 2-thioxo-2,3-dihydro-1H-quinazolin-4-one 
• 48141-61-3 2,4-bis(methylthio)quinazoline 

Downstream Products

• 149847-79-0 DL 017 
• 180959-12-0 (S)-(+)-3-?(4-(2-methoxyphenyl)piperazin-1-yl)methyl-5-methylthio-2,3-dihydroimidazo[1,2-c]quinazoline 

Relevant articles and documents

Studies on quinazolines. 6. Asymmetric synthesis of (S)-(+)- and (R)-(-)-3-[[4-(2-methoxyphenyl)piperazin-1-yl]methyl]-5-methylthio-2,3- dihydroimidazo[1,2-c]quinazolines

The titled compounds have been synthesized in five steps from commercially available (R)-(+) and (S)-(-)-glycidol. The overall yield was about 29% with ee>98.5%. Copyright