180972-00-3Relevant academic research and scientific papers
Cyclic carbopalladation of alkynes terminated by carbonylative amidation
Coperet, Christophe,Ma, Shengming,Sugihara, Takumichi,Negishi, Ei-Ichi
, p. 11529 - 11544 (2007/10/03)
Termination of cyclic carbopalladation of alkynes via carbonylative lactamization can be achieved more satisfactorily with alkenyl or aryl halides containing an ω-carboxamido or ω-sulfonamido group than with those containing an ω-amino group. The method appears to be generally satisfactory for the preparation of fused cyclic systems consisting of six-membered rings, while the other cases require further development.
Termination of carbopalladation of alkynes via carbonylative amidation producing lactams
Coperet, Christophe,Sugihara, Takumichi,Negishi, Ei-Ichi
, p. 1771 - 1774 (2007/10/02)
Trapping of acylpalladium derivatives can be achieved using internal carboxamides and sulfonamides, in addition to simple amines and applied to termination of carbopalladation to produce lactams.
