18106-76-8

Basic information

• Product Name: Phosphinic acid, benzoylphenyl-, methyl ester
• CAS NO: 18106-76-8
• Molecular Formula: C14H13O3P
• Molecular Weight: 260.229
• Mol File: 18106-76-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphinic acid, benzoylphenyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphinic acid, benzoylphenyl-, methyl ester(18106-76-8)
• EPA Substance Registry System: Phosphinic acid, benzoylphenyl-, methyl ester(18106-76-8)

Safety Data

• Hazardous Substances Data: 18106-76-8(Hazardous Substances Data)

Upstream product

• 18351-42-3 dimethyl phenylphosphonite 
• 98-88-4 benzoyl chloride 

Downstream Products

• 1620195-86-9 (α,α-difluoro-benzyl)-phenyl-phosphinic acid methyl ester 
• 100-47-0 benzonitrile 
• 67446-05-3 C₇H₈O₃P^(1-)*K⁽¹⁺⁾ 
• 10088-45-6 methyl phenylphosphonic acid 
• 2628-93-5 N-benzoyl(phenyl)phosphonamidate 
• 129950-74-9 methyl α-hydroxyiminobenzyl(phenyl)phosphinate 
• 132509-04-7 (Z)-methyl α-hydroxyiminobenzyl(phenyl)phosphinate 
• 129950-74-9 (E)-methyl α-hydroxyiminobenzyl(phenyl)phosphinate 

Relevant articles and documents

Stereoselectivity in Fragmentation and Rearrangement of α-Hydroxyiminophosphinates and -phosphonates. A Synthetic Approach to Acylphosphon- and phosphor-amidates. Crystal Structures of Methyl (E)-α-Hydroxyiminobenzylphenylphosphinate and Methyl Benzoylphenylphosphonamidate

Reaction of methyl benzoylphenylphosphinate 1 with hydroxylamine gave methyl α-hydroxyiminobenzylphenylphosphinate 2 as a mixture of E and Z isomers with the E isomer predominating.Pure (E)-2 when heated gave methyl N-benzoylphenylphosphonamidate 3 as the sole product.In contrast, (Z)-2 when heated gave, as a result of fragmentation, mainly methyl hydrogen phenylphosphonate 4 and benzonitrile, together with methyl N-phenylcarbamoylphenylphosphinate 5 as the minor product; the latter results from Beckmann rearrangement of (Z)-2.Analogous behaviour is exhibited by the two geometrical isomers of dimethyl α-hydroxyiminobenzylphenylphosphinate (E)-2 and methyl benzoylphenylphosphonamidate 3 are reported.