18351-42-3

Basic information

• Product Name: Phosphorous acid, dimethyl phenyl ester
• CAS NO: 18351-42-3
• Molecular Formula: C8H11O3P
• Molecular Weight: 186.147
• Mol File: 18351-42-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Phosphorous acid, dimethyl phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphorous acid, dimethyl phenyl ester(18351-42-3)
• EPA Substance Registry System: Phosphorous acid, dimethyl phenyl ester(18351-42-3)

Safety Data

• Hazardous Substances Data: 18351-42-3(Hazardous Substances Data)

Upstream product

• 20217-54-3 dimethoxy(dimethylamino)phosphine 
• 868-85-9 Dimethyl phosphite 
• 108-95-2 phenol 
• 67-56-1 methanol 
• 7719-12-2 phosphorus trichloride 
• 101-02-0 triphenyl phosphite 
• 121-45-9 phosphorous acid trimethyl ester 
• 122194-07-4 dimethyl N,N-diisopropylphosphoramidite 
• 20621-25-4 dimethoxy(diethylamino)phosphine 
• 3426-89-9 phenyl phosphorodichloridite 

Downstream Products

• 75-25-2 Bromoform 
• 117098-97-2 bromophosphoric acid methyl ester-phenyl ester 
• 7526-25-2 methyl phenyl methylphosphonate 
• 32674-76-3 2,2,4-Trimethyl-4-(methyl-phenoxy-phosphinoyl)-3-oxo-pentanoic acid methyl ester 
• 32674-88-7 2,2,4-Trimethyl-3-(methyl-phenoxy-phosphinoyloxy)-pent-3-enoic acid methyl ester 
• 32674-87-6 3-(Methoxy-methyl-phosphinoyloxy)-2,2,4-trimethyl-pent-3-enoic acid phenyl ester 
• 121-45-9 phosphorous acid trimethyl ester 
• 96-36-6 methyl phosphite 
• 84812-11-3 dimethyl phenyl phosphite ozonide 
• 16390-98-0 methyl phenyl H-phosphonate 
• 1231709-89-9 C₂₆H₂₇N₂O₇P 
• 1231710-05-6 C₃₁H₂₉N₂O₇P 
• 868-85-9 Dimethyl phosphite 
• 347860-45-1 [1-(diphenoxyphosphonyl)-1-hydroxyethyl]-1-phosphonic acid methyl phenyl ester 

Relevant articles and documents

Site-specific functionalisation of proteins by a Staudinger-type reaction using unsymmetrical phosphites

Unsymmetrical phosphites react efficiently in a Staudinger reaction with p-azido-phenylalanine, which can be applied for the biotinylation of proteins, thereby expanding the scope of the chemoselective Staudinger-phosphite reaction of aryl azides with symmetrical phosphites to the corresponding phosphoramidates. The Royal Society of Chemistry 2010.

DIARYL ALKYLPHOSPHONATES AND METHODS FOR PREPARING SAME

A method for preparing substantially pure optionally substituted diaryl alkylphosphonates from an optionally substituted triarylphosphite and an optionally substituted trialkylphosphite or an optionally substituted alkanol under special reaction conditions is described.

Phosphitylation via the Mitsunobu reaction

Treatment of a dialkyl phosphite with triphenylphosphine and diisopropyl azodicarboxylate in toluene, followed by addition of an alcohol, results in the formation of the corresponding trialkyl phosphite. Similarly, dialkyl phosphonites can be synthesised from monoalkyl phosphites (alkyl phosphinates).