181224-97-5

Upstream product

• 1191-99-7 2,3-dihydro-2H-furan 
• 501-52-0 3-Phenylpropionic acid 

Downstream Products

• 5371-52-8 2-hydroxytetrahydrofuran 
• 16133-83-8 tetrahydro-2-phenylfuran 
• 1083-30-3 dihydrochalcone 
• 6880-25-7 1,1,3-triphenylpropan-1-ol 
• 40463-09-0 4-methyl-1-phenylpentan-3-one 
• 20795-51-1 1-phenylpentan-3-one 
• 1985-60-0 1-phenyl-3-ethylpentan-3-ol 
• 5195-24-4 4,4-dimethyl-1-phenylpentan-3-one 
• 19965-73-2 <2-Phenyl-aethyl>-di-tert-butyl-carbinol 
• 181225-04-7 1-phenyl-4-nonyn-3-one 

Relevant academic research and scientific papers

Kinetics and mechanism of the hydrolysis of tetrahydro-2-furyl and tetrahydropyran-2-yl alkanoates

The kinetics and mechanism of the hydrolysis of tetrahydro-2-furyl and tetrahydropyran-2-yl alkanoates in water and water-20% ethanol are reported. In acidic and neutral media, kinetics, activation parameters, 18O isotope exchange studies, substituent effects, solvent effects and the lack of buffer catalysis point clearly to an AA1-1 mechanism with formation of the tetrahydro-2-furyl or tetrahydropyran-2-yl carbonium ion as the rate-limiting step. There is no evidence of a base-promoted BAC-2 mechanism up to pH 12.