40463-09-0

Basic information

• Product Name: 4-methyl-1-phenylpentan-3-one
• Synonyms: 4-methyl-1-phenylpentan-3-one;1-Phenyl-4-methyl-3-pentanone;2-Methyl-5-phenyl-3-pentanone;4-Methyl-1-phenyl-3-pentanone
• CAS NO: 40463-09-0
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.25484
• EINECS: 254-930-9
• Mol File: 40463-09-0.mol
• Article Data: 42

Chemical Properties

• Boiling Point: 254.8 °C at 760 mmHg
• Flash Point: 101 °C
• Appearance: /
• Density: 0.948 /cm³
• Vapor Pressure: 0.0169mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: 4-methyl-1-phenylpentan-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-1-phenylpentan-3-one(40463-09-0)
• EPA Substance Registry System: 4-methyl-1-phenylpentan-3-one(40463-09-0)

Safety Data

• Hazardous Substances Data: 40463-09-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H16O/c1-10(2)12(13)9-8-11-6-4-3-5-7-11/h3-7,10H,8-9H2,1-2H3

Upstream product

• 60550-54-1 2-methyl-5-phenylpent-1-en-3-one 
• 79-31-2 isobutyric Acid 
• 501-52-0 3-Phenylpropionic acid 
• 68426-07-3 (+/-)-1-phenyl-5-methylpentan-3-ol 
• 40463-08-9 2,2-dimethyl-3-(2-phenylethyl)oxirane 
• 3277-89-2 phenethylmagnesium bromide 
• 25179-23-1 lithium dimethylacetate 
• 3160-32-5 4-methyl-1-phenyl-1-penten-3-one 
• 98611-98-4 N-(3-methylbutan-2-ylidene)-1-phenylmethanamine 
• 100-46-9 benzylamine 
• 108-86-1 bromobenzene 
• 71385-30-3 methyl 3-hydroxy-4-methyl-2-methylenepentanoate 
• 104-53-0 3-phenyl-propionaldehyde 
• 563-80-4 3-methyl-butan-2-one 

Downstream Products

• 260257-61-2 (RS)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid tert-butyl ester 
• 23936-97-2 (±)2,4-dimethyl-1-phenylpentan-3-one 
• 20627-49-0 3-phenyl-propionic acid butyl ester 
• 263842-78-0 5-trifluoromethyl-pyridine-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-70-2 N-[5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-4-trifluoromethyl-benzenesulfonamide 
• 263842-71-3 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-3-cyano-benzenesulfonamide 
• 263842-72-4 N-[5-tert-Butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-4-cyano-benzenesulfonamide 
• 263842-75-7 pyridine-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-74-6 thiophene-2-sulfonic acid [5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-amide 
• 263842-97-3 pyridine-2-sulfonic acid 5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl ester 
• 263842-98-4 pyridine-3-sulfonic acid 5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl ester 
• 263842-69-9 N-[5-tert-butyl-4-(4-hydroxy-6-isopropyl-2-oxo-6-phenethyl-5,6-dihydro-2H-pyran-3-ylsulfanyl)-2-methyl-phenyl]-methanesulfonamide 
• 260257-94-1 3-(2-tert-butyl-4-hydroxy-5-methyl-phenylsulfanyl)-4-hydroxy-6-isopropyl-6-phenethyl-5,6-dihydro-pyran-2-one 
• 260257-62-3 (S)-3-hydroxy-3-(2-phenethyl)-4-methylpentanoic acid 

Relevant articles and documents

Catalytic Radical Trifluoromethylalkynylation of Unactivated Alkenes

The trifluoromethylalkynylation of unactivated alkenes with alkynyl sulfones and Togni's reagent was developed. The reaction was catalyzed by 2,4,6-trimethylpyridine, leading to various β-trifluoromethylated alkynes under metal-free conditions with a broad substrate scope and wide functional group compatibility. A mechanism involving catalytic nonchain radical processes is proposed.

Visible-Light Decatungstate/Disulfide Dual Catalysis for the Hydro-Functionalization of Styrenes

We describe an efficient photoredox system, relying on decatungstate/disulfide catalysts, for the hydrofunctionalization of styrenes. In this methodology the use of disulfide as a cocatalyst was shown to be crucial for the reaction efficiency. This photoredox system was employed for the hydro-carbamoylation, -acylation, -alkylation, and -silylation of styrenes, giving access to a large variety of useful building blocks and high-value molecules such as amides and unsymmetrical ketones from simple starting materials.

Visible-Light-Promoted Catalytic Ring-Opening Isomerization of 1,2-Disubstituted Cyclopropanols to Linear Ketones

Isomerization to linear ketones is a valuable transformation of 1,2-disubstituted cyclopropanols proceeding through radical intermediates. Despite simplicity of this reaction, the known protocol required stoichiometric amounts of both an oxidant and a reducing agent. In this article, we report a catalytic isomerization of 1,2-disubstituted cyclopropanols to linear ketones enabled by the photoredox catalytic system consisting of an acridinium photocatalyst and diphenyl disulfide under irradiation with blue LEDs.