181230-63-7Relevant academic research and scientific papers
Synthesis of a cancer growth-inhibiting diterpene-stereoselective formal synthesis of (+)-aphidicolin
Toyota, Masahiro,Nishikawa, Youichi,Fukumoto, Keiichiro
, p. 10347 - 10362 (1996)
Stereoseletive formal synthesis of the diterpene tetraol (+)-aphidicolin (1) is described employing as key steps the cycloisomerization of the enyne 9 to provide the bicyclo[3.2.1]octane derivative 8 and the intramolecular Diels-Alder reaction of the trie
Enantioselective Total Synthetic Route to (+)-Aphidicolin
Toyota, Masahiro,Nishikawa, Youichi,Fukumoto, Keiichiro
, p. 5379 - 5382 (1995)
Enantioselective total synthetic route to (+)-aphidicolin (1) has been described.Cycloisomerization reaction (9->10) and intramolecular Diels-Alder reaction (12->13) were employed for the key steps of the sequence.
