18133-46-5

Basic information

• Product Name: α-(3,4-dimethoxyphenyl)acetoacetonitrile
• CAS NO: 18133-46-5
• Molecular Weight: 219.24
• Mol File: 18133-46-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: α-(3,4-dimethoxyphenyl)acetoacetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: α-(3,4-dimethoxyphenyl)acetoacetonitrile(18133-46-5)
• EPA Substance Registry System: α-(3,4-dimethoxyphenyl)acetoacetonitrile(18133-46-5)

Safety Data

• Hazardous Substances Data: 18133-46-5(Hazardous Substances Data)

Upstream product

• 2466-76-4 N-Acetylimidazole 
• 93-17-4 3,4-dimethoxyphenylacetonitrile 
• 141-78-6 ethyl acetate 

Downstream Products

• 134993-16-1 α-(3,4-dimethoxyphenyl)-α-(2-methyl-1,3-dithiolan-2-yl)acetonitrile 
• 130423-56-2 6-methyl-2-ethyl-5-(3,4-dimethoxyphenyl)-4-oxo-1,3-oxazinium perchlorate 
• 347840-95-3 3-methyl-4-(3,4-dimethoxyphenyl)-1H-5-aminopyrazole 
• 1346260-38-5 (E)-1-(3,4-dimethoxyphenyl)-2-(methoxyimino)propan-1-one 
• 71367-49-2 1-(3,4-dimethoxyphenyl)propane-1,2-dione 
• 1331858-82-2 C₁₅H₁₉NO₃ 
• 1369597-15-8 1-(3,4-dimethoxyphenyl)-5,6-dimethoxy-2-methyl-1H-indene-1,3-dicarbonitrile 
• 132576-21-7 5-amino-4-(3,4-dimethoxyphenyl)-3-methyl-1-phenyl-1H-pyrazole 

Relevant articles and documents

Stereoselective C?C Oxidative Coupling Reactions Photocatalyzed by Zwitterionic Ligand Capped CsPbBr3 Perovskite Quantum Dots

Semiconductor quantum dots (QDs) have attracted tremendous attention in the field of photocatalysis, owing to their superior optoelectronic properties for photocatalytic reactions, including high absorption coefficients and long photogenerated carrier lifetimes. Herein, by choosing 2-(3,4-dimethoxyphenyl)-3-oxobutanenitrile as a model substrate, we demonstrate that the stereoselective (>99 %) C?C oxidative coupling reaction can be realized with a high product yield (99 %) using zwitterionic ligand capped CsPbBr3 perovskite QDs under visible light illumination. The reaction can be generalized to different starting materials with various substituents on the phenyl ring and varied functional moieties, producing stereoselective dl-isomers. A radical mediated reaction pathway has been proposed. Our study provides a new way of stereoselective C?C oxidative coupling via a photocatalytic means using specially designed perovskite QDs.

PYRAZOLO[1,5-A]TRIAZIN-4-AMINE DERIVATIVES USEFUL IN THERAPY

A compound of formula (I), or a pharmaceutically acceptable salt thereof, useful in therapy, in particular in the treatment of a viral infection.

Deacylative allylation: Allylic alkylation via retro-Claisen activation

A new method for allylic alkylation of a variety of relatively nonstabilized carbon nucleophiles is described herein. In this process of "deacylative allylation", the coupling partners, an allylic alcohol and a ketone pronucleophile, undergo in situ retro-Claisen activation to generate an allylic acetate and a carbanion. In the presence of palladium, these reactive intermediates undergo catalytic coupling to form a new C-C bond. In comparison to unimolecular decarboxylative allylation, a commonly utilized method for allylation of carbon anions, deacylative allylation is an intermolecular process. Moreover, deacylative allylation allows the direct coupling of readily available allylic alcohols. Lastly, the full utility of deacylative allylation is demonstrated by the rapid construction of a variety 1,6-heptadienes via 3-component couplings.