18139-63-4

Usage

Molecular structure

A chemical compound consisting of a thiophene ring with a chlorodimethylsilyl group attached to the 2-position.

Common uses

Used as a building block in organic synthesis, particularly in the production of materials for electronics and photonics.

Protecting group

The chlorodimethylsilyl group acts as a protecting group for the thiophene ring, allowing for selective reactions to occur at other positions on the molecule.

Stability

Known for its stability and its ability to participate in a variety of chemical reactions.

Value in research

A valuable tool for researchers and chemists working in the field of organic chemistry.

Upstream product

• 5713-61-1 thiophen-2-yl magnesium bromide 
• 75-78-5 dimethylsilicon dichloride 
• 23395-45-1 dimethyl-thiophen-2-yl-silane 
• 188290-36-0 thiophene 
• 107-05-1 3-chloroprop-1-ene 
• 624-65-7 2-propynyl chloride 
• 1003-09-4 2-bromothiophene 
• 96-43-5 2-thienyl chloride 

Downstream Products

• 192990-73-1 5-formyl-2-thienyl-5-[(4-dimethylaminophenyl)-(E)-vinyl]-2-thienyldimethylsilane 
• 857350-22-2 (E,E)-[4-(dimethyl-2-thienylsilyl)-1,3-butadienyl]benzonitrile 
• 492-97-7 2,2'-Bithiophene 
• 124733-28-4 1,1,3,3-tetramethyl-1,3-bis(2'-thienyl)disiloxane 

Relevant academic research and scientific papers

METHOD FOR PRODUCING ARYLSILANE COMPOUND CONTAINING HALOSILANE COMPOUND AS RAW MATERIAL

PROBLEM TO BE SOLVED: To provide a method for producing an arylsilane compound with low production cost. SOLUTION: A method for producing an arylsilane compound includes a reaction step for the cross-coupling reaction of a halosilane compound represented by general formula (A-1), (A-2), or (A-3) and an arylboronic acid pinacol ester in the presence of a nickel catalyst, a Lewis acid catalyst, and an organic base (R independently represent an aromatic hydrocarbon group, a heteroaromatic ring group, or a C1-20 hydrocarbon group; X independently represent a halogeno group or a trifluoromethanesulfonyloxy group). SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

Synthesis of novel conjugated oligomers for second-order nonlinear optics: Incorporation of a central spacer as a conjugation modulator

A new series of second-order nonlinear optical chromophores has been synthesized that consists of a conjugated segment end-capped with an electron acceptor and an electron donor, respectively and a central spacer intended to modulate the electro-optical e

Comparative study of new and known thienyl derivatives of ene-yne benzylamine as mammalian squalene epoxidase inhibitors

Analogs of the well-known squalene epoxidase inhibitor (SE) NB-598 (2) have been prepared and tested as cholesterol biosynthesis inhibitors in HepG2 cells. Among the compounds tested, the vinylthiophene analog 4 and the tertiary amide derivative of thiophene 8 emerged as potent human SE inhibitors and probably bind to the enzyme in a very similar manner as NB-598 (2). Surprisingly enough, compounds 4 and 8, contrary to NB-598, are poor inhibitors of rat SE, thus further demonstrating major differences between mammalian enzymes from different species.

Electrochemical synthesis of bis(2-thienyl) silanes, 2-thienylchlorosilanes, bis[5-(2-bromothienyl)]silanes, and 5-(2-bromothienyl) dimethylchlorosilane, precursors of poly[(silanylene) thiophene]s

Bis(2-thienyl)silanes and bis[5-(2-bromothienyl)]silanes were synthesized by electrochemical reduction of monohalothiophenes (Br,C1) and 2,5-dibromothiophene respectively in the presence of a dichlorosilane in THF or DME, using an undivided cell, a sacrif