18143-06-1

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 86-29-3 Diphenylacetonitrile 

Downstream Products

• 33925-53-0 2-Benzoyl-2,2-diphenylacetonitrile 
• 128445-57-8 2-(4-Methylbenzoyl)-2,2-diphenylacetonitrile 
• 59021-27-1 (E)-3-Hydroxy-2,2,5-triphenyl-pent-4-enenitrile 
• 59021-18-0 (E)-3-Methyl-2,2-diphenyl-5-trimethylsilanyloxy-pent-4-enenitrile 
• 59021-17-9 3-(4-Chloro-phenyl)-2,2-diphenyl-3-trimethylsilanyloxy-propionitrile 
• 59021-16-8 2,2,3-Triphenyl-3-trimethylsilanyloxy-propionitrile 
• 59021-29-3 2,2,3-Triphenyl-3-trimethylsilanyloxy-butyronitrile 
• 59021-21-5 3-Methyl-2,2-diphenyl-3-trimethylsilanyloxy-butyronitrile 
• 59021-22-6 3-Methyl-2,2,4-triphenyl-3-trimethylsilanyloxy-butyronitrile 
• 101877-34-3 (+/-)-4-hydroxy-2,2-diphenylvaleronitril 
• 59021-24-8 3-(4-Chloro-phenyl)-3-hydroxy-2,2-diphenyl-propionitrile 
• 59021-26-0 5,5-Dimethoxy-3-methyl-2,2-diphenyl-pentanenitrile 
• 59021-32-8 3-Hydroxy-3-methyl-2,2,4-triphenyl-butyronitrile 
• 59021-23-7 3-Hydroxy-2,2,3-triphenyl-propionitrile 

Relevant academic research and scientific papers

Efficient aldol-type reaction of o-protected α-Hydroxy Aldehydes and N-Trimethylsilyl ketene imines: Synthesis of β,γ-Dihydroxy-Nitriles

An uncatalyzed aldol-type reaction of aromatic N-trimethylsilyl ketene imines with O-protected α-trialkylsilyloxy or α-benzyloxy aldehydes is reported. It is shown that N-trimethylsilyl ketene imines (SKIs) are essential for the success of this aldol-type

Method for preparing gamma-alcoholic compound containing nitrile group

The invention discloses a method for preparing a gamma-alcoholic compound containing a nitrile group, and belongs to the technical field of organic synthesis. The method comprises the steps that a nitrile-based compound containing alpha-H is mixed with me