181486-39-5

Basic information

• Product Name: (S)-2-{1-[4-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-4-methyl-2,6-dioxo-cyclohexylidene]-ethylamino}-3-phenyl-propionic acid methyl ester
• Synonyms: (S)-2-{1-[4-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-4-methyl-2,6-dioxo-cyclohexylidene]-ethylamino}-3-phenyl-propionic acid methyl ester
• CAS NO: 181486-39-5
• Molecular Weight: 534.609
• Mol File: 181486-39-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-2-{1-[4-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-4-methyl-2,6-dioxo-cyclohexylidene]-ethylamino}-3-phenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-{1-[4-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-4-methyl-2,6-dioxo-cyclohexylidene]-ethylamino}-3-phenyl-propionic acid methyl ester(181486-39-5)
• EPA Substance Registry System: (S)-2-{1-[4-((S)-1-Methoxycarbonyl-2-phenyl-ethylcarbamoyl)-4-methyl-2,6-dioxo-cyclohexylidene]-ethylamino}-3-phenyl-propionic acid methyl ester(181486-39-5)

Safety Data

• Hazardous Substances Data: 181486-39-5(Hazardous Substances Data)

Upstream product

• 181486-35-1 3-Acetoxy-1-methyl-5-oxo-cyclohex-3-enecarboxylic acid methyl ester 
• 181486-36-2 4-acetyl-3,5-dioxo-1-methylcyclohexane carboxylic acid methyl ester 
• 181486-34-0 3,5-dioxo-1-methylcyclohexane carboxylic acid methyl ester 
• 78640-30-9 methyl 3,5-dimethoxy-1-methylcyclohexa-2,5-diene-1-carboxylate 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Downstream Products

• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 

Relevant articles and documents

A new linker for primary amines applicable to combinatorial approaches

We describe a new linker molecule (ADCC-linker) for the attachment of primary amines to solid support. The linker is stable towards acidic conditions (eg. TFA) basic conditions (eg. piperidine, DBU) as well as towards uronium type coupling reagents. The amine can be quantitatively released from the support using a 2% hydrazine in DMF solution.