18159-23-4Relevant articles and documents
Design and synthesis of non-peptide mimetics mapping the immunodominant myelin basic protein (MBP83-96) epitope to function as T-cell receptor antagonists
Yannakakis, Mary-Patricia,Simal, Carmen,Tzoupis, Haralambos,Rodi, Maria,Dargahi, Narges,Prakash, Monica,Mouzaki, Athanasia,Platts, James A.,Apostolopoulos, Vasso,Tselios, Theodore V.
, (2017/06/19)
Encephalitogenic T cells are heavily implicated in the pathogenesis of multiple sclerosis (MS), an autoimmune demyelinating disease of the central nervous system. Their stimulation is triggered by the formation of a trimolecular complex between the human
Palladium-Catalyzed Regioselective Dehydrogenative C–H/C–H Cross-Coupling of Pyrroles and Pyridine N-Oxides
Liu, Shanshan,Tzschucke, C. Christoph
supporting information, p. 3509 - 3513 (2016/07/28)
The palladium-catalyzed cross-dehydrogenative coupling of N-alkylpyrroles and pyridine N-oxides gave the corresponding pyrrolylpyridine N-oxides. Cu(OAc)2·H2O as a co-catalyst with air as the terminal oxidant led to preferential coupling in the β-position, whereas AgOAc as the stoichiometric oxidant resulted in preferential coupling in the α-position. N-(Benzyloxymethyl)pyrrole derivatives were deprotected by hydrogenolysis followed by basic hydrolysis.
Synthesis of 2-(N-benzylpyrrolyl)-benzimidazoles using polyphosphoric acid prompted cyclocondensation
Mochona, Bereket,Le, Laine,Gangapuram, Madhavi,Mateeva, Nelly,Ardley, Tiffany,Redda, Kinfe K.
experimental part, p. 1367 - 1371 (2010/12/29)
Synthesis of a series of 2-substituted benzimidazoles was carried out for screening anti-inflammatory activities. 2-(N-benzylpyrrolyl)-benzimidazoles 9a-k were synthesized from N-benzyl-2-pyrrole carboxylic acids 8a-d and 4-substituted-1,2-phenylenediamin
