18167-41-4

Usage

Uses

Used in Pharmaceutical Research:
2-(Allyloxy)benzohydrazide is used as a reagent in pharmaceutical research for its diverse biological activities, including antifungal, antimicrobial, and antitubercular properties. Its potential as an antiparasitic and anticancer agent is also being explored, making it a valuable compound in the development of new drugs and treatments for various diseases.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(Allyloxy)benzohydrazide is used as a key intermediate for the synthesis of various organic compounds. Its unique structure and reactivity make it a versatile building block for the preparation of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Anticancer Applications:
2-(Allyloxy)benzohydrazide is being investigated for its potential as an anticancer agent due to its ability to inhibit the growth of tumor cells. It may be used as a lead compound in the development of new cancer therapies, offering a promising avenue for research in oncology.
Used in Antifungal and Antimicrobial Applications:
2-(Allyloxy)benzohydrazide has demonstrated antifungal and antimicrobial properties, making it a potential candidate for use in the development of new antifungal and antimicrobial agents. It can be used in various applications, such as in the treatment of fungal infections or as a preservative in various industries.
Used in Antitubercular Applications:
Given its antitubercular properties, 2-(Allyloxy)benzohydrazide is being explored for its potential use in the development of new treatments for tuberculosis. Its ability to target and inhibit the growth of Mycobacterium tuberculosis, the causative agent of tuberculosis, makes it a valuable compound in the search for more effective therapies against this disease.

Upstream product

• 6282-42-4 methyl 2-allyloxybenzoate 
• 119-36-8 methyl salicylate 
• 74618-13-6 1-acetyl-2-(o-allyloxy)benzoyl-1-p-tolylsulfonylhydrazine 
• 52542-42-4 2-allyloxybenzoyl chloride 
• 59086-52-1 2-allyloxybenzoic acid 
• 74618-09-0 2--1-(p-tolylsulfonyl)hydrazine 

Relevant academic research and scientific papers

Recyclable CuO nanoparticles-catalyzed synthesis of novel-2,5-disubstituted 1,3,4-oxadiazoles as antiproliferative, antibacterial, and antifungal agents

A series of new 2,5-disubstituted 1,3,4-oxadiazoles have been conveniently synthesized through an oxidative C-O coupling by direct C-H bond activation of N-aroyl-N-arylidinehydrazines using a catalytic quantity of CuO nanoparticles. Twenty compounds have been synthesized in good to excellent yields (75-90 %). All the synthesized compounds were evaluated for their in vitro antiproliferative, antibacterial, and antifungal activity. Compounds 8d and 10d are more promising antiproliferative agents with IC50 value of 3.66 and 3.89 μM in MCF-7 cell line, and compounds 8a and 10a were showed more potent antifungal activity than standard drug.

Acyl hydrazines as precursors to acyl radicals

The use of acyl hydrazines (hydrazides) as precursors for the stoichiometric generation of acyl radicals is explored. Two classes of substrates are examined: unsubstituted acyl hydrazines and acyl hydrazines substituted with a leaving group (2-nitrobenzenesulfonyl or 'nosyl'). Both types are successfully converted to acyl radicals, and are then trapped by nitroxide radicals to give acyloxyamine products. Cyclization reactions are demonstrated for both classes of substrates. A low temperature modification of the McFayden-Stevens reaction is also developed.

Intramolecular Cycloaddition Reactions of N-Sulfonyl Nitrile Imides Bearing Alkenyl Groups

The reaction of the p-tolyl(or phenyl)sulfonylhydrazones of some 2-(alkenyloxy)benzaldehydes with lead tetraacetate leads, via the nitrile imide intermediates, Ar-C(+)=N-N(-)-SO2-C6H4-X-p, to intramolecular 1,3-dipolar cycloadducts and 1-acetyl-2-aroyl-1-