18175-21-8 Usage
Uses
Used in Organic Synthesis:
(3E)-4-(4-iodophenyl)but-3-en-2-one is used as a reagent in organic synthesis for its unique structure and aromatic properties. It is commonly used in the production of various aromatic compounds and pharmaceuticals.
Used in Pharmaceutical Industry:
(3E)-4-(4-iodophenyl)but-3-en-2-one is used as a key intermediate in the synthesis of pharmaceuticals due to its unique structure and reactivity. It has been studied for its potential applications in the development of new drugs and materials.
Used in Chemical Research:
(3E)-4-(4-iodophenyl)but-3-en-2-one is used as a research compound in the field of organic chemistry to study its properties, reactivity, and potential applications in the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 18175-21-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,1,7 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 18175-21:
(7*1)+(6*8)+(5*1)+(4*7)+(3*5)+(2*2)+(1*1)=108
108 % 10 = 8
So 18175-21-8 is a valid CAS Registry Number.
18175-21-8Relevant articles and documents
RhIII-Catalyzed Synthesis of Highly Substituted 2-Pyridones using Fluorinated Diazomalonate
Das, Debapratim,Sahoo, Gopal,Biswas, Aniruddha,Samanta, Rajarshi
supporting information, p. 360 - 364 (2020/01/25)
A RhIII-catalyzed strategy was developed for the rapid construction of highly substituted 2-pyridone scaffolds using α,β-unsaturated oximes and fluorinated diazomalonate. The reaction proceeds through direct, site-selective alkylation based on migratory insertion and subsequent cyclocondensation. A wide substrate scope with different functional groups was explored. The requirement of fluorinated diazomalonate was explored for this transformation. The developed methodology was further extended with the synthesis of the bioactive compound.
