181827-49-6 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-chloro-4-fluoro-5-methylphenyl)ethan-1-one is used as an intermediate for the synthesis of various pharmaceuticals due to its unique chemical structure and reactivity. Its ability to be incorporated into the development of new drugs makes it a valuable asset in this field.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(2-chloro-4-fluoro-5-methylphenyl)ethan-1-one is utilized as a key component in the creation of different agrochemicals. Its properties allow it to contribute to the effectiveness of these products, which are designed to enhance crop protection and yield.
Used in Organic Synthesis:
1-(2-chloro-4-fluoro-5-methylphenyl)ethan-1-one is employed as a building block in organic synthesis, where it is used to construct more complex molecules. Its versatility and stability make it a preferred choice for researchers and chemists working on developing new organic compounds.
Used in Industrial Processes:
1-(2-chloro-4-fluoro-5-methylphenyl)ethan-1-one can be found in several industrial processes, where it is used for its specific chemical properties to facilitate the production of various products. Its stability and reactivity under normal conditions make it a reliable component in these processes.
Check Digit Verification of cas no
The CAS Registry Mumber 181827-49-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,1,8,2 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 181827-49:
(8*1)+(7*8)+(6*1)+(5*8)+(4*2)+(3*7)+(2*4)+(1*9)=156
156 % 10 = 6
So 181827-49-6 is a valid CAS Registry Number.
181827-49-6Relevant academic research and scientific papers
HETEROCYCLIC DERIVATIVES AND USE THEREOF
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Page/Page column 30, (2016/06/28)
A heterocyclic derivative represented by formula (I), or a pharmaceutically acceptable salt or a stereoisomer thereof, which has an inhibitory effect on the activation of STAT3 protein, and is useful for the prevention or treatment of diseases associated
Synthesis of substituted phenyl ketones via Pd-catalysed hydrodechlorination of their polychlorinated derivatives
Bomben, Andrea,Marques, Carlos A.,Selva, Maurizio,Tundo, Pietro
, p. 1109 - 1114 (2007/10/03)
The following compounds, 2- and 3-methylacetophenones, 2- and 3-methylbenzophenones, and 2,2'-, 2,3'- and 3,3'-dimethylbenzophenones have been synthesized through a Pd-catalysed hydrodechlorination of the corresponding dichlorinated derivatives. The reaction has been carried out under multiphase conditions at 30-50°C, by bubbling H2 at atmospheric pressure into a biphasic system constituted by an organic substrate solution (isooctane solvent) and an aqueous alkaline solution (50% aq KOH), in the presence of Pd/C (5% wt) and Aliquat 336 (tricaprylylmethylammonium chloride). Likewise, fluorinated aceto- and benzophenones (4-fluoro-3-methylacetophenone and 4-fluoro-3-methylbenzo-, 4-fluoro-2',3-dimethylbenzo-, 4-fluoro-3,3'-dimethylbenzophenones) have been prepared starting from the corresponding chlorinated methylfluoro and dimethyfluoro ketones. Under such conditions, the presence of the onium salt allows the reaction to proceed with a high chemoselectivity: chlorine is removed while both the reduction of the carbonyl group and/or fluorine removal are prevented.
